C1655
Cholera Toxin B subunit
FITC conjugate, lyophilized powder
Sinónimos:
CTB
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About This Item
Productos recomendados
conjugado
FITC conjugate
Nivel de calidad
Formulario
lyophilized powder
mol peso
~12 kDa
composición
Protein, ~20% Lowry
Extensión del etiquetado
~1.0 mol FITC per mol protein
temp. de almacenamiento
2-8°C
cadena SMILES
CCOc1ccccc1C(=O)Nc2ccc(Cl)c(c2)C(F)(F)F
InChI
1S/C16H13ClF3NO2/c1-2-23-14-6-4-3-5-11(14)15(22)21-10-7-8-13(17)12(9-10)16(18,19)20/h3-9H,2H2,1H3,(H,21,22)
Clave InChI
YDXZSNHARVUYNM-UHFFFAOYSA-N
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Aplicación
Cholera Toxin B subunit-fluorescein isothiocyanate (FITC) conjugate has been used as a fluorescent tracer:
- to label distal cerebrospinal fluid-contacting neurons (dCSF-CNs) in lateral ventricles of rat
- to stain epididymal sperms of mice
- to stain peritoneal macrophages of mice
Acciones bioquímicas o fisiológicas
The cholera toxin B subunit is used for track tracing in neurological research, taking advantage of GM1 ganglioside binding and retrograde transport. Tissue culture cells treated with cholera toxin are not killed and tissues of animals do not become necrotic.
Características y beneficios
This compound is a featured product for Cyclic Nucleotide research. Click here to discover more featured Cyclic Nucleotide products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.
Forma física
Lyophilized powder containing Tris buffer salts, sodium chloride, sodium EDTA and sodium azide
Nota de análisis
Activity measured by ELISA using ganglioside GM1 coated multiwell plates, rabbit anti-cholera toxin B subunit antibodies, and peroxidase-labeled goat anti-rabbit IgG as the second antibody. 50% saturation of binding was achieved with 0.01-1 μg of the cholera toxin B subunit-FITC conjugate per mL.
Palabra de señalización
Warning
Frases de peligro
Consejos de prudencia
Clasificaciones de peligro
Acute Tox. 4 Inhalation - Aquatic Chronic 3
Código de clase de almacenamiento
11 - Combustible Solids
Clase de riesgo para el agua (WGK)
WGK 2
Punto de inflamabilidad (°F)
Not applicable
Punto de inflamabilidad (°C)
Not applicable
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