P3075

Phenylarsine oxide

≥97%, powder

• Sinónimos: Arzene, Oxophenylarsine, PAO
• Fórmula empírica (notación de Hill): C₆H₅AsO
• Número de CAS: 637-03-6
• Peso molecular: 168.02
• Beilstein: 2935227
• Número CE: 211-275-3
• Número MDL: MFCD00001990
• Código UNSPSC: 12352119
• ID de la sustancia en PubChem: 24898387
• NACRES: NA.77

Propiedades

• origen biológico: synthetic (organic)
• Ensayo: ≥97%
• Formulario: powder
• color: white to off-white
• mp: 145-148 °C
• solubilidad: DMSO: 50 mg/mL
• cadena SMILES: O=[As]c1ccccc1
• InChI: 1S/C6H5AsO/c8-7-6-4-2-1-3-5-6/h1-5H
• Clave InChI: BQVCCPGCDUSGOE-UHFFFAOYSA-N

Descripción

Descripción general

Phenylarsine oxide (PhAsO⁴) is a bifunctional SH group chemical. It is hydrophobic in nature.

Aplicación

Phenylarsine oxide has been used to infuse animals with a nigrostriatal transection, to determine whether peroxovanadium (pVa) would synergize with brain-derived neurotrophic factor (BDNF).

Acciones bioquímicas o fisiológicas

Phenylarsine oxide inhibits internalization of cell surface receptors; inhibits tyrosine phosphatases, with no effect on tyrosine kinase. Metabolic poison.

Phenylarsine oxide (PAO) can reduce the motility and sustainability of Setaria cervi. It has the ability to stimulate cyclosporin A-sensitive transition in the presence of EGTA (ethylene glycol-bis(β-aminoethyl ether)-N,N,N′,N′-tetraacetic acid). It acts as a stimulator of mitochondrial ion fluxes.

Características y beneficios

This compound is featured on the Phosphoprotein Phosphatases (Tyrosine) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Información de seguridad

• Pictogramas: GHS06,GHS09
• Palabra de señalización: Danger
• Frases de peligro: H301 + H331,H410
• Consejos de prudencia: P261 - P264 - P271 - P273 - P301 + P310 - P304 + P340 + P311
• Clasificaciones de peligro: Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 1
• Código de clase de almacenamiento: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• Clase de riesgo para el agua (WGK): WGK 3
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable