636010

3,5-Dimethylpyrazole-4-boronic acid pinacol ester

97%

• Sinónimos: 3,5-Dimethyl-4-(4,4,5,5-tetramethyl-1,3,2dioxaborolan-2-yl)-1H-pyrazole, 3,5-Dimethyl-4-pyrazoleboronic acid pinacol ester
• Fórmula empírica (notación de Hill): C₁₁H₁₉BN₂O₂
• Número de CAS: 857530-80-4
• Peso molecular: 222.09
• Número MDL: MFCD05663852
• Código UNSPSC: 12352103
• ID de la sustancia en PubChem: 24882751
• NACRES: NA.22

Propiedades

• Ensayo: 97%
• Formulario: solid
• mp: 163-168 °C (lit.)
• cadena SMILES: Cc1n[nH]c(C)c1B2OC(C)(C)C(C)(C)O2
• InChI: 1S/C11H19BN2O2/c1-7-9(8(2)14-13-7)12-15-10(3,4)11(5,6)16-12/h1-6H3,(H,13,14)
• Clave InChI: GNUDAJTUCJEBEI-UHFFFAOYSA-N

Descripción

Aplicación

3,5-Dimethylpyrazole-4-boronic acid pinacol ester can be used:

• To synthesize 9H-pyrimido[4,5-b]indole and aryl-benzimidazole based BET bromodomain and extra terminal (BET) protein inhibitors.
• To prepare naphthalimide based photo-exchangeable photochromic fluorescent molecules.
• As a reactant to develop DNA-encoded chemical libraries by palladium-catalyzed Suzuki coupling reaction with DNA-linked aryl halides.

Información de seguridad

• Código de clase de almacenamiento: 11 - Combustible Solids
• Clase de riesgo para el agua (WGK): WGK 3
• Equipo de protección personal: dust mask type N95 (US), Eyeshields, Gloves