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Merck

ADRB2

adrenoceptor beta 2, surface

Sinónimos:
ADRB2R, ADRBR, B2AR, BAR, BETA2AR
Especie:
ID UniProtKB:
ID del gen:
  • Human(154) Summary: This gene encodes beta-2-adrenergic receptor which is a member of the G protein-coupled receptor superfamily. This receptor is directly associated with one of its ultimate effectors, the class C L-type calcium channel Ca(V)1.2. This receptor-channel complex also contains a G protein, an adenylyl cyclase, cAMP-dependent kinase, and the counterbalancing phosphatase, PP2A. The assembly of the signaling complex provides a mechanism that ensures specific and rapid signaling by this G protein-coupled receptor. This gene is intronless. Different polymorphic forms, point mutations, and/or downregulation of this gene are associated with nocturnal asthma, obesity and type 2 diabetes. [provided by RefSeq, Jul 2008]
  • Mouse(11555) adrenergic receptor, beta 2
  • Rat(24176) adrenoceptor beta 2, surface
  • domestic guinea pig(100722663) adrenoceptor beta 2, surface
  • naked mole-rat(101708921) adrenoceptor beta 2, surface
  • sheep(100170320) adrenoceptor beta 2, surface
  • Domestic Rabbit(100340821) adrenoceptor beta 2, surface
  • chicken(427623) adrenergic, beta-2-, receptor, surface
  • domestic cat(493767) adrenoceptor beta 2, surface
  • cow(281605) adrenergic, beta-2-, receptor, surface
  • Horse(100060659) adrenoceptor beta 2, surface
  • dog(403910) adrenoceptor beta 2, surface

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Small Molecule - Agonist

Referencia del producto
Descripción
Especie
(−)-Isoproterenol hydrochloride, ,
Especie
human
Clenbuterol hydrochloride, ≥95%,
Especie
human
Salbutamol, ,
Especie
human
Formoterol fumarate dihydrate, >98% (HPLC),
Especie
human
Fenoterol hydrobromide, ,
Especie
human

Small Molecule - Antagonist

Referencia del producto
Descripción
Especie
ICI 118,551 hydrochloride, ≥98% (HPLC), powder,
Especie
human
Propranolol hydrochloride, United States Pharmacopeia (USP) Reference Standard,
Especie
human
Timolol maleate, United States Pharmacopeia (USP) Reference Standard,
Especie
human
Propranolol hydrochloride solution, 1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®,
Especie
human
Propranolol for system suitability, European Pharmacopoeia (EP) Reference Standard,
Especie
human

Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-ADRB2 antibody produced in rabbit, affinity isolated antibody,
Reactividad de especies
human, mouse, rat
Aplicación
ELISA
immunofluorescence

western blot
Anti-ADRB2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunohistochemistry
Anti-β-2 Adrenergic Receptor antibody produced in chicken, affinity isolated antibody, buffered aqueous solution,
Reactividad de especies
human
Aplicación
western blot
Anti-Adrenergic Receptor β2 antibody produced in rabbit, affinity isolated antibody,
Reactividad de especies
human
Aplicación
ELISA
immunofluorescence

immunohistochemistry

western blot
Anti-phospho-Adrenergic Receptor B2 (pSer355+Ser356) antibody produced in rabbit, affinity isolated antibody,
Reactividad de especies
human, mouse, rat
Aplicación
ELISA
immunohistochemistry

western blot

Small Molecule - Blocker

Referencia del producto
Descripción
Especie
Sotalol hydrochloride, United States Pharmacopeia (USP) Reference Standard,
Especie
human
Sotalol hydrochloride, British Pharmacopoeia (BP) Reference Standard,
Especie
human
(±)-Sotalol hydrochloride, ≥98% (TLC), powder,
Especie
human
(S)-(−)-Propranolol hydrochloride, ≥98% (TLC), powder,
Especie
human
Propafenone hydrochloride, United States Pharmacopeia (USP) Reference Standard,
Especie
human

esiRNA

Referencia del producto
Descripción
Especie
MISSION® esiRNA, targeting mouse Adrb2,
Especie
mouse
MISSION® esiRNA, targeting human ADRB2,
Especie
human