E5750

Ergocalciferol

40,000,000 USP units/g

• Synonym(e): Bestrahltes Ergosterol, Calciferol, Ercalciol, Ergosterol, bestrahlt, Vitamin D₂
• Empirische Formel (Hill-System): C₂₈H₄₄O
• CAS-Nummer: 50-14-6
• Molekulargewicht: 396.65
• Beilstein: 1916682
• EG-Nummer: 200-014-9
• MDL-Nummer: MFCD00166988
• UNSPSC-Code: 12352205
• eCl@ss: 34058017
• PubChem Substanz-ID: 24894344
• NACRES: NA.79

Eigenschaften

• Biologische Quelle: synthetic (organic)
• Qualitätsniveau: 200
• Assay: ≥97%
• Form: powder
• Spezifische Aktivität: 40,000,000 USP units/g
• Methode(n): HPLC: suitable
• Farbe: white to off-white
• mp (Schmelzpunkt): 114-118 °C (lit.)
• Lagertemp.: 2-8°C
• SMILES String: CC(C)[C@@H](C)/C=C/[C@@H](C)[C@@]1([H])CC[C@@]([C@]1(C)CCC/2)([H])C2=C\C=C(C[C@@H](O)CC3)/C3=C
• InChI: 1S/C28H44O/c1-19(2)20(3)9-10-22(5)26-15-16-27-23(8-7-17-28(26,27)6)12-13-24-18-25(29)14-11-21(24)4/h9-10,12-13,19-20,22,25-27,29H,4,7-8,11,14-18H2,1-3,5-6H3/b10-9+,23-12+,24-13-/t20-,22+,25-,26+,27-,28+/m0/s1
• InChIKey: MECHNRXZTMCUDQ-RKHKHRCZSA-N
• Angaben zum Gen: human ... VDR(7421)

Beschreibung

Allgemeine Beschreibung

Vitamin D₂ or ergocalciferol is available through dietary supplements or plant sources. It is a provitamin, which is fat-soluble.

Anwendung

Ergocalciferol has been used as a component of the diet for rats, to study its bioavailability from ultraviolet-irradiated D2-rich yeast. It has also been used as a standard for identification and quantification of vitamins, as part of a study to determine the nutritional composition of food fishes.

Biochem./physiol. Wirkung

Ergocalciferol (vitamin D₂) and 25-Hydroxycholecalciferol (vitamin D₃) are the two forms of vitamin D, which are activated in vivo by hydroxylation. Vitamin D2 and D3 may be used in a wide range of studies to assess their effects on function such as immune function and calcium homeostasis.

Ergocalciferol is used for antirachitic treatment. Vitamin D has an active role in bone mineralization. Severe deficiency of this vitamin has been associated with osteomalacia and rickets.

Verpackung

Verschweisste Ampulle

Menge

1 USP unit = 1 I.U.

Sicherheitshinweise

• Piktogramme: GHS06,GHS08
• Signalwort: Danger
• H-Sätze: H301 + H311,H330,H372
• P-Sätze: P260 - P264 - P280 - P302 + P352 + P312 - P304 + P340 + P310 - P314
• Gefahreneinstufungen: Acute Tox. 2 Inhalation - Acute Tox. 3 Dermal - Acute Tox. 3 Oral - STOT RE 1 Oral
• Lagerklassenschlüssel: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges