1294820

Glutathione

United States Pharmacopeia (USP) Reference Standard

• Sinonimo/i: L-Glutathione reduced, γ-L-Glutamyl-L-cysteinyl-glycine, GSH
• Formula condensata: H₂NCH(CO₂H)CH₂CH₂CONHCH(CH₂SH)CONHCH₂CO₂H
• Numero CAS: 70-18-8
• Peso molecolare: 307.32
• Beilstein: 1729812
• Numero MDL: MFCD00065939
• Codice UNSPSC: 41116107
• ID PubChem: 329749948
• NACRES: NA.24

Proprietà

• Grado: pharmaceutical primary standard
• Famiglia di API: glutathione
• Produttore/marchio commerciale: USP
• Punto di fusione: 192-195 °C (dec.) (lit.)
• applicazioni: pharmaceutical (small molecule)
• Formato: neat
• Stringa SMILE: N[C@@H](CCC(=O)N[C@@H](CS)C(=O)NCC(O)=O)C(O)=O
• InChI: 1S/C10H17N3O6S/c11-5(10(18)19)1-2-7(14)13-6(4-20)9(17)12-3-8(15)16/h5-6,20H,1-4,11H2,(H,12,17)(H,13,14)(H,15,16)(H,18,19)/t5-,6-/m0/s1; RWSXRVCMGQZWBV-WDSKDSINSA-N

Descrizione

Amino Acid Sequence

γ-Glu-Cys-Gly

Descrizione generale

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

Applicazioni

May be used at 5-10 mM to elute glutathione S-transferase (GST) from glutathione agarose.

Azioni biochim/fisiol

Endogenous antioxidant that plays a major role in reducing reactive oxygen species formed during cellular metabolism and the respiratory burst. Glutathione-S-transferase catalyzes the formation of glutathione thioethers with xenobiotics, leukotrienes, and other molecules that have an electrophilic center. Glutathione also forms disulfide bonds with cysteine residues in proteins. Via these mechanisms, it can have the paradoxical effect of reducing the efficacy of anti-cancer agents.

Risultati analitici

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Altre note

Sales restrictions may apply.

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 11 - Combustible Solids
• Classe di pericolosità dell'acqua (WGK): WGK 2
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable