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Key Documents

G6529

Sigma-Aldrich

L-Glutathione reduced

≥98.0%, BioXtra

Sinonimo/i:

γ-L-Glutamyl-L-cysteinyl-glycine, GSH

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About This Item

Formula condensata:
H2NCH(CO2H)CH2CH2CONHCH(CH2SH)CONHCH2CO2H
Numero CAS:
Peso molecolare:
307.32
Beilstein:
1729812
Numero CE:
Numero MDL:
Codice UNSPSC:
12352209
ID PubChem:
NACRES:
NA.26

product name

L-Glutathione reduced, BioXtra, ≥98.0%

Nome Commerciale

BioXtra

Livello qualitativo

Saggio

≥98.0%

Forma fisica

powder

Impurezze

≤0.02% Phosphorus (P)
≤0.1% Insoluble matter

Residuo alla calcinazione

≤0.1%

Colore

white

Punto di fusione

192-195 °C (dec.) (lit.)

Solubilità

H2O: 0.1 M, clear, colorless

Anioni in tracce

sulfate (SO42-): ≤0.05%

Cationi in tracce

Al: ≤0.0005%
Ca: ≤0.02%
Cu: ≤0.0005%
Fe: ≤0.001%
K: ≤0.005%
Mg: ≤0.001%
NH4+: ≤0.05%
Na: ≤0.005%
Pb: ≤0.001%
Zn: ≤0.0005%

Temperatura di conservazione

2-8°C

Stringa SMILE

N[C@@H](CCC(=O)N[C@@H](CS)C(=O)NCC(O)=O)C(O)=O

InChI

1S/C10H17N3O6S/c11-5(10(18)19)1-2-7(14)13-6(4-20)9(17)12-3-8(15)16/h5-6,20H,1-4,11H2,(H,12,17)(H,13,14)(H,15,16)(H,18,19)/t5-,6-/m0/s1
RWSXRVCMGQZWBV-WDSKDSINSA-N

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Amino Acid Sequence

γ-Glu-Cys-Gly

Applicazioni

May be used at 5-10 mM to elute glutathione S-transferase (GST) from glutathione agarose.

Azioni biochim/fisiol

Endogenous antioxidant that plays a major role in reducing reactive oxygen species formed during cellular metabolism and the respiratory burst. Glutathione-S-transferase catalyzes the formation of glutathione thioethers with xenobiotics, leukotrienes, and other molecules that have an electrophilic center. Glutathione also forms disulfide bonds with cysteine residues in proteins. Via these mechanisms, it can have the paradoxical effect of reducing the efficacy of anti-cancer agents.

Prodotti correlati

N° Catalogo
Descrizione
Determinazione del prezzo

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 2

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

Eyeshields, Gloves, type N95 (US)


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Articoli

Antioxidants protect biological systems from oxidative damage produced by oxygen-containing free radicals and from redoxactive transition metal ions such as iron, copper, and cadmium.

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