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G6013

Sigma-Aldrich

L-Glutathione reduced

≥98.0%, suitable for cell culture, BioReagent

Sinonimo/i:

Glutathione, Reduced, γ-L-Glutamyl-L-cysteinyl-glycine, GSH

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About This Item

Formula condensata:
H2NCH(CO2H)CH2CH2CONHCH(CH2SH)CONHCH2CO2H
Numero CAS:
70-18-8
Peso molecolare:
307.32
Beilstein:
1729812
Numero CE:
200-725-4
Numero MDL:
MFCD00065939
Codice UNSPSC:
12352209
ID PubChem:
24895241
NACRES:
NA.26

product name

L-Glutathione reduced, suitable for cell culture, BioReagent, ≥98.0%, powder

Nome Commerciale

BioReagent

Saggio

≥98.0%

Forma fisica

powder

tecniche

cell culture | mammalian: suitable

Colore

white

Punto di fusione

192-195 °C (dec.) (lit.)

Solubilità

H2O: 50 mg/mL

Temperatura di conservazione

2-8°C

Stringa SMILE

N[C@@H](CCC(=O)N[C@@H](CS)C(=O)NCC(O)=O)C(O)=O

InChI

1S/C10H17N3O6S/c11-5(10(18)19)1-2-7(14)13-6(4-20)9(17)12-3-8(15)16/h5-6,20H,1-4,11H2,(H,12,17)(H,13,14)(H,15,16)(H,18,19)/t5-,6-/m0/s1
RWSXRVCMGQZWBV-WDSKDSINSA-N

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Categorie correlate

Amino Acid Sequence

γ-Glu-Cys-Gly

Applicazioni

May be used at 5-10 mM to elute glutathione S-transferase (GST) from glutathione agarose.

Azioni biochim/fisiol

Endogenous antioxidant that plays a major role in reducing reactive oxygen species formed during cellular metabolism and the respiratory burst. Glutathione-S-transferase catalyzes the formation of glutathione thioethers with xenobiotics, leukotrienes, and other molecules that have an electrophilic center. Glutathione also forms disulfide bonds with cysteine residues in proteins. Via these mechanisms, it can have the paradoxical effect of reducing the efficacy of anti-cancer agents.

Prodotti correlati

N° Catalogo
Descrizione
Determinazione del prezzo

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 2

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

Eyeshields, Gloves, type N95 (US)

Certificati d'analisi (COA)

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The New phytologist, 208(2), 507-518 (2015-05-15)
Plant-invading microbes betray their presence to a plant by exposure of antigenic molecules such as small, secreted proteins called 'effectors'. In Fusarium oxysporum f. sp. lycopersici (Fol) we identified a pair of effector gene candidates, AVR2-SIX5, whose expression is controlled
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Nature chemical biology, 5(5), 341-343 (2009-03-31)
Here we describe a method for the site-selective attachment of synthetic molecules into specific 'endogenous' proteins in vivo using ligand-directed tosyl (LDT) chemistry. This approach was applied not only for chemically labeling proteins in living cells, tissues and mice but
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One or more effectors in the labial saliva (LS) of generalist Noctuid caterpillars activate plant signaling pathways to modulate jasmonate (JA)-dependent defense responses; however, the exact mechanisms involved have yet to be elucidated. A potential candidate in this phytohormone interplay
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FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 29(6), 2281-2291 (2015-02-15)
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Articoli

Dietary Antioxidants

Antioxidants protect biological systems from oxidative damage produced by oxygen-containing free radicals and from redoxactive transition metal ions such as iron, copper, and cadmium.

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