1091108

Capsaicin

United States Pharmacopeia (USP) Reference Standard

• Sinonimo/i: 8-Methyl-N-vanillyl-trans-6-nonenamide
• Formula condensata: (CH₃)₂CHCH=CH(CH₂)₄CONHCH₂C₆H₃-4-(OH)-3-(OCH₃)
• Numero CAS: 404-86-4
• Peso molecolare: 305.41
• Beilstein: 2816484
• Numero MDL: MFCD00017259
• Codice UNSPSC: 41116107
• ID PubChem: 329749225
• NACRES: NA.24

Proprietà

• Grado: pharmaceutical primary standard
• Famiglia di API: capsaicin
• Produttore/marchio commerciale: USP
• Punto di fusione: 62-65 °C (lit.)
• applicazioni: pharmaceutical (small molecule)
• Formato: neat
• Temperatura di conservazione: 2-8°C
• Stringa SMILE: COc1cc(CNC(=O)CCCC\C=C\C(C)C)ccc1O
• InChI: 1S/C18H27NO3/c1-14(2)8-6-4-5-7-9-18(21)19-13-15-10-11-16(20)17(12-15)22-3/h6,8,10-12,14,20H,4-5,7,9,13H2,1-3H3,(H,19,21)/b8-6+; YKPUWZUDDOIDPM-SOFGYWHQSA-N
• Informazioni sul gene: human ... TRPV1(7442)

Descrizione

Descrizione generale

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Applicazioni

Capsaicin USP reference standard for use in specified quality tests and assays.

Also used to prepare standard solutions for the assay, identification, composition and strength analysis according to the given below monographs of United States Pharmacopeia (USP):

• Capsaicin
• Capsicum Oleoresin
• Capsicum
• Ginger Tincture

Azioni biochim/fisiol

Prototype vanilloid receptor agonist. Neurotoxin; activates sensory neurons that give rise to unmyelinated C-fibers, many of which contain substance P. Topical application desensitizes the sensory nerve endings giving a paradoxical antinociceptive effect; systemic administration can be neurotoxic to capsaicin-sensitive cells, especially in newborn animals. Active component of chili peppers.

Risultati analitici

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Altre note

Sales restrictions may apply.

Informazioni sulla sicurezza

• Pittogrammi: GHS06,GHS08,GHS05
• Avvertenze: Danger
• Indicazioni di pericolo: H300,H315,H317,H318,H334,H335
• Consigli di prudenza: P280 - P301 + P310 + P330 - P302 + P352 - P305 + P351 + P338 + P310
• Classi di pericolo: Acute Tox. 2 Oral - Eye Dam. 1 - Resp. Sens. 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3
• Organi bersaglio: Respiratory system
• Codice della classe di stoccaggio: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• Classe di pericolosità dell'acqua (WGK): WGK 3
• Punto d’infiammabilità (°F): 235.4 °F - closed cup
• Punto d’infiammabilità (°C): 113 °C - closed cup