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Documenti fondamentali

U2875

Sigma-Aldrich

Uric acid sodium salt

Sinonimo/i:

2,6,8-Trihydroxypurine, Sodium acid urate

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About This Item

Formula condensata:
C5H3N4O3Na
Numero CAS:
Peso molecolare:
190.09
Numero CE:
Numero MDL:
Codice UNSPSC:
41106305
ID PubChem:
NACRES:
NA.51

Origine biologica

microbial
synthetic

Livello qualitativo

Saggio

11.0-13.0% anhydrous basis (Sodium, ICP)

Stato

powder

Solubilità

1 M NaOH: 25 mg/mL, clear, colorless to faintly yellow

Stringa SMILE

[Na].O=C1NC(=O)C2=C(N1)NC(=O)N2

InChI

1S/C5H4N4O3.Na.H/c10-3-1-2(7-4(11)6-1)8-5(12)9-3;;/h(H4,6,7,8,9,10,11,12);;
IHMJZGFANDMEJM-UHFFFAOYSA-N

Applicazioni

Uric acid sodium salt has been used in isotonic solution of NaCl dose titration study. It has been used as a suspension in NaCl for intra-articular administration to experimental animals to induce synovitis.

Azioni biochim/fisiol

Sodium urate is the sodium salt of uric acid. In gout, it is observed in synovial fluid. Sodium urate has been shown to precipitate calcium oxalate from urine. It is also known to reverse the inhibitory effects of reactive oxygen and nitrogen metabolites on gelatinase A activity. Excess sodium urate in soft tissues results in a condition referred to as tophi.

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

Eyeshields, Gloves, type N95 (US)


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Cerebral infarction (CI) is a common clinical cerebrovascular disease, and to explore the pathophysiological mechanisms and seek effective treatment means are the hotspot and difficult point in medical research nowadays. Numerous studies have confirmed that uric acid plays an important
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