Passa al contenuto
Merck
Tutte le immagini(1)

Documenti fondamentali

Visualizza tutta la documentazione

T0261

Sigma-Aldrich

Thiamphenicol

Sinonimo/i:

Raceophenidol, Thiophenicol, D-threo-2,2-Dichloro-N-(β-hydroxy-α-[hydroxymethyl]-4-[methylsulfonyl]phenethyl)acetamide

Autenticatiper visualizzare i prezzi riservati alla tua organizzazione & contrattuali
Tutte le immagini(1)

About This Item

Formula empirica (notazione di Hill):
C12H15Cl2NO5S
Numero CAS:
15318-45-3
Peso molecolare:
356.22
Beilstein:
2819542
Numero CE:
239-355-3
Numero MDL:
MFCD00467983
Codice UNSPSC:
51284303
ID PubChem:
24899874
NACRES:
NA.85

Stato

powder

Livello qualitativo

100

Colore

white to off-white

Solubilità

ethanol: soluble 50 mg/mL

Spettro attività antibiotica

Gram-negative bacteria
Gram-positive bacteria

Modalità d’azione

protein synthesis | interferes

Stringa SMILE

CS(=O)(=O)c1ccc(cc1)[C@@H](O)[C@@H](CO)NC(=O)C(Cl)Cl

InChI

1S/C12H15Cl2NO5S/c1-21(19,20)8-4-2-7(3-5-8)10(17)9(6-16)15-12(18)11(13)14/h2-5,9-11,16-17H,6H2,1H3,(H,15,18)/t9-,10-/m1/s1
OTVAEFIXJLOWRX-NXEZZACHSA-N

Cerchi prodotti simili? Visita Guida al confronto tra prodotti

Descrizione generale

Chemical structure: phenicole

Applicazioni

Thiamphenicol is an antibiotic that has been used to treat chancroid in men and uncomplicated gonorrhea. It is used in studies of bacterial protein synthesis at the level of peptidyl transferase activity associated with the 23S rRNA of the 50S ribosomal subunit. It is used to study chloraniphenicol-thiamphenicol-resistance and the use of fluorinated analogs when resistance is encountered.

Azioni biochim/fisiol

Thiamphenicol inhibits mitochondrial protein synthesis of proteins such as cytochrome c oxidase.

Confezionamento

1G,5G,25G

Altre note

Keep container tightly closed in a dry and well-ventilated place.

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 2

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

Eyeshields, Gloves, type N95 (US)

Scegli una delle versioni più recenti:

Certificati d'analisi (COA)

Lot/Batch Number
STBK4118
STBK0885
STBK0559
STBJ9974
STBJ4207

Non trovi la versione di tuo interesse?

Se hai bisogno di una versione specifica, puoi cercare il certificato tramite il numero di lotto.

Cerca un COA

Possiedi già questo prodotto?

I documenti relativi ai prodotti acquistati recentemente sono disponibili nell’Archivio dei documenti.

Visita l’Archivio dei documenti

I clienti hanno visto anche

Slide 1 of 9

1 of 9

Furazolidone

Sigma-Aldrich

F9505

Furazolidone

Cloramfenicolo VETRANAL®, analytical standard

Supelco

31667

Cloramfenicolo

Cloramfenicolo ≥98% (HPLC)

Sigma-Aldrich

C0378

Cloramfenicolo

D-Cycloserine synthetic

Sigma-Aldrich

C3909

D-Cycloserine

Terfenadine

Sigma-Aldrich

T9652

Terfenadine

Trimethoprim ≥98.5%

Sigma-Aldrich

T7883

Trimethoprim

Cloramfenicolo BioReagent, suitable for plant cell culture

Sigma-Aldrich

C1919

Cloramfenicolo

Anhydrotetracycline hydrochloride VETRANAL®, analytical standard

Supelco

37919

Anhydrotetracycline hydrochloride

Clarithromycin ≥95% (HPLC)

Sigma-Aldrich

C9742

Clarithromycin

D R Rezende et al.
Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment, 29(4), 559-570 (2012-01-14)
A validated method based on European and Brazilian legislation is reported. It is applicable to the simultaneous determination of chloramphenicol (CAP) and florfenicol (FF) by LC-MS/MS in liquid milk, milk powder and bovine muscle. The chromatographic analysis is completed in
Weixin Tao et al.
Applied and environmental microbiology, 78(17), 6295-6301 (2012-07-04)
Chloramphenicol and florfenicol are broad-spectrum antibiotics. Although the bacterial resistance mechanisms to these antibiotics have been well documented, hydrolysis of these antibiotics has not been reported in detail. This study reports the hydrolysis of these two antibiotics by a specific
Sanaz Pilehvar et al.
Analytical chemistry, 84(15), 6753-6758 (2012-06-26)
A novel, label-free folding induced aptamer-based electrochemical biosensor for the detection of chloramphenicol (CAP) in the presence of its analogues has been developed. CAP is a broad-spectrum antibiotic that has lost its favor due to its serious adverse toxic effects
V P Syriopoulou et al.
Antimicrobial agents and chemotherapy, 19(2), 294-297 (1981-02-01)
We evaluated the in vitro antimicrobial activity of Sch 24893, Sch 25298, and Sch 25393, three novel analogs of chloramphenicol and thiamphenicol. All of the analogs had minimal inhibitory concentrations of less than or equal to 10 micrograms/ml for 18
T E Tupasi et al.
The British journal of venereal diseases, 59(3), 172-175 (1983-06-01)
The use of cefuroxime and thiamphenicol in uncomplicated gonococcal infection was studied in 562 women confined to a clinic to preclude reinfection before cultural confirmation of cure. Cefuroxime was as effective as spectinomycin in the treatment of infections due to
Visualizza tutti i documenti correlati

Il team dei nostri ricercatori vanta grande esperienza in tutte le aree della ricerca quali Life Science, scienza dei materiali, sintesi chimica, cromatografia, discipline analitiche, ecc..

Contatta l'Assistenza Tecnica.