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Documenti fondamentali

32492

Supelco

Florfenicol amine

VETRANAL®, analytical standard

Sinonimo/i:

R)-α-[(1S)-1-Amino-2-fluoroethyl]-4-(methylsulfonyl)benzenemethanol, D-(−)-threo-2-Amino-3-fluoro-1-[4-(methylsulfonyl)phenyl]-1-propanol

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About This Item

Formula empirica (notazione di Hill):
C10H14FNO3S
Numero CAS:
Peso molecolare:
247.29
Numero MDL:
Codice UNSPSC:
41116107
ID PubChem:
NACRES:
NA.24

Grado

analytical standard

Livello qualitativo

Nome Commerciale

VETRANAL®

Durata

limited shelf life, expiry date on the label

tecniche

HPLC: suitable
gas chromatography (GC): suitable

applicazioni

forensics and toxicology
pharmaceutical (small molecule)

Formato

neat

Stringa SMILE

CS(=O)(=O)c1ccc(cc1)[C@@H](O)[C@H](N)CF

InChI

1S/C10H14FNO3S/c1-16(14,15)8-4-2-7(3-5-8)10(13)9(12)6-11/h2-5,9-10,13H,6,12H2,1H3/t9-,10-/m1/s1
XLSYLQDVLAXIKK-NXEZZACHSA-N

Descrizione generale

Florfenicol amine is a polar metabolite of florfenicol.

Applicazioni

Florfenicol amine may be used as an analytical reference standard for the determination of the analyte in:
  • Poultry and porcine muscle and liver by gas chromatography-negative chemical ionization mass spectrometry (GC-NCI/MS) with selected ion monitoring (SIM) detection.
  • Food samples by ultra-high performance liquid chromatography-electrospray ionization-tandem mass spectrometry (UHPLC-ESI-MS/MS) operating in selected reaction monitoring (SRM) detection mode.
  • Chicken muscle by LC-ESI-MS/MS with multiple reaction monitoring (MRM) detection.

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Prodotti consigliati

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

Note legali

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

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Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3


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Certificati d'analisi (COA)

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B-K Park et al.
Journal of veterinary pharmacology and therapeutics, 30(1), 32-36 (2007-01-16)
The pharmacokinetics of florfenicol and its active metabolite florfenicol amine were investigated in rabbits after a single intravenous (i.v.) and oral (p.o.) administration of florfenicol at 20 mg/kg bodyweight. The plasma concentrations of florfenicol and florfenicol amine were determined simultaneously
Determination of chloramphenicol, thiamphenicol, florfenicol, and florfenicol amine in poultry and porcine muscle and liver by gas chromatography-negative chemical ionization mass spectrometry.
Shen J, et al.
Journal of Chromatography. B, Biomedical Sciences and Applications, 877(14-15), 1523-1529 (2009)
Simultaneous determination and confirmation of chloramphenicol, thiamphenicol, florfenicol and florfenicol amine in chicken muscle by liquid chromatography-tandem mass spectrometry.
Zhang S, et al.
Journal of Chromatography. B, Biomedical Sciences and Applications, 875(2), 399-404 (2008)
Pengjie Luo et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 878(2), 207-212 (2009-10-28)
A rapid and sensitive liquid chromatography-electrospray ionization-tandem mass spectrometry (LC-ESI-MS/MS) method to quantify thiamphenicol (TAP), florfenicol (FF), and florfenicol amine (FFA) in swine muscle is described. An immunoaffinity chromatography (IAC) column based on polyclonal antibodies and protein A-sepharose CL 4B
Jin-E Wu et al.
Journal of agricultural and food chemistry, 56(18), 8261-8267 (2008-08-20)
Florfenicol (FF) is a broad-spectrum antibiotic used increasingly in aquaculture, livestock, and poultry to treat diseases. To avoid using labor-intensive instrumental methods to detect residues of FF in food and food products, a simple and convenient indirect competitive enzyme-linked immunosorbent

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