SML1172

FFN102

≥98% (HPLC)

• Sinonimo/i: 4-(2-Amino-ethyl)-6-chloro-7-hydroxy-chromen-2-one trifluoroacetate, 4-(2-Aminoethyl)-6-chloro-7-hydroxy-2H-1-benzopyran-2-one trifluoroacetate, Mini 102, Mini102
• Formula empirica (notazione di Hill): C₁₁H₁₀ClNO₃ · CF₃CO₂H
• Numero CAS: 1234064-11-9
• Peso molecolare: 353.68
• Codice UNSPSC: 12352200
• ID PubChem: 329825700
• NACRES: NA.77

Proprietà

• Livello qualitativo: 100
• Saggio: ≥98% (HPLC)
• Forma fisica: powder
• Condizioni di stoccaggio: desiccated
• Colore: white to light brown
• Solubilità: DMSO: 10 mg/mL, clear
• Temperatura di conservazione: 2-8°C
• Stringa SMILE: FC(F)(F)C(O)=O.NCCC(C1=CC(Cl)=C(O)C=C1O2)=CC2=O
• InChI: 1S/C11H10ClNO3.C2HF3O2/c12-8-4-7-6(1-2-13)3-11(15)16-10(7)5-9(8)14;3-2(4,5)1(6)7/h3-5,14H,1-2,13H2;(H,6,7); OGHPXKAKVMJGQH-UHFFFAOYSA-N

Descrizione

Azioni biochim/fisiol

FFN102 is a pH-responsive fluorescent false neurotransmitter that acts as a dopamine transporter substrate (DAT) and also a substrate for vesicular monoamine transporter 2 (VMAT2). FFN102 selectively labels dopamine cell bodies and dendrites in ventral midbrain and dopaminergic synaptic terminals in dorsal striatum. Its greater fluorescence emission in neutral than acidic environments allows the visualization of dopamine release at individual presynaptic terminals and in situ pH measurement of catecholamine secretory vesicles.

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 11 - Combustible Solids
• Classe di pericolosità dell'acqua (WGK): WGK 3
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable