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Key Documents

GERPN6301

Thiourea

Cytiva RPN6301, pack of 100 g

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About This Item

Codice UNSPSC:
41105323
NACRES:
NA.77

Forma fisica

solid

Caratteristiche

wetted part: no

Confezionamento

pack of 100 g

Produttore/marchio commerciale

Cytiva RPN6301

Colore

White

Intervallo di pH

5-7

Solubilità

cold water: soluble (Soluble in cold water and hot water)
diethyl ether: soluble (Partially soluble in diethyl ether)
methanol: soluble (Easily soluble in methanol)

Descrizione generale

Thiourea is a chaotrope used together with urea in the IPG strip rehydration to solubilize and denature proteins, and improve the solubility of membrane proteins.

Applicazioni

Thiourea has been used as a component of lysis buffer for solubilization of the proteins from tissue samples and T-leukemia cells. It has also been used as a component of sample buffer for placental tissue, leaf proteome, and 2D electrophoresis.

Azioni biochim/fisiol

Thiourea is an organic compound and its derivatives have antibacterial, antiviral, antifungal and insecticidal property. It is actively used in the drug development against human immunodeficiency virus (HIV) and hepatitis C infection. Thiourea inhibits cyclooxygenase enzyme and effectively reduces prostaglandin E2 (PGE2) and thromboxane (TXB2) production and is antithrombotic in human platelets. It is cytotoxic to vaginal epithelial cells and may function as potent spermicidal agent. Thiourea based derivatives of anticancer drug sorafenib, eliclits antiproliferative activity in human colon cancer cell line, HCT116 cells.

Stoccaggio e stabilità

Please be aware this product may be shipped 90 days before the expiration date. For more information on the batch specific expiration date, please contact technical service.

Risultati analitici

To view the Certificate of Analysis for this product, please visit www.cytiva.com.

Pittogrammi

Environment
GHS09

Avvertenze

Warning

Indicazioni di pericolo

H302,H361d,H351,H411

Codice della classe di stoccaggio

13 - Non Combustible Solids

Certificati d'analisi (COA)

Cerca il Certificati d'analisi (COA) digitando il numero di lotto/batch corrispondente. I numeri di lotto o di batch sono stampati sull'etichetta dei prodotti dopo la parola ‘Lotto’ o ‘Batch’.

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DL-Ditiotreitolo suitable for electrophoresis, ≥99%

Sigma-Aldrich

D9163

DL-Ditiotreitolo

N-metil-D-glucamina 99.0-100.5% (titration)

Sigma-Aldrich

M2004

N-metil-D-glucamina

Iodoacetamide BioUltra

Sigma-Aldrich

I1149

Iodoacetamide

Urea powder, BioReagent, for molecular biology, suitable for cell culture

Sigma-Aldrich

U5378

Urea

Novel thiourea compounds as dual-function microbicides
D?Cruz, OJ, et al.
Biology of Reproduction, 63(1), 196-205 (2000)
Synthesis and antiplatelet activity of antithrombotic thiourea compounds: biological and structure-activity relationship studies
Lourencco A, et al.
Molecules (Basel), 20(4), 7174-7200 (2015)
Synthesis, Characterization, Biological Activity and Use of Thiourea Derivative (PhTTU) Studies of dinitrate-1-phenyl-3-(thiazol-2-yl)-2-thioureato Cd (II) ion Complex
Alfallous KA and Aburzeza MM
International Journal of Scientific Research, 4(6) (2015)
Capabilities using 2-D DIGE in proteomics research
Tissue proteomics, 1-18 (2008)
Spontaneous Unexplained Preterm Labor with Intact Membrane: Finding Protein Biomarkers through Placenta Proteome
Electrophoresis-Life Sciences Practical Applications (2018)
Visualizza tutti i documenti correlati

Articoli

Components of Rehydration Solution

This page describes components of rehydration solutions for use in 2-D Electrophoresis with GE Healthcare products.

Protocolli

Rehydration Solutions

Rehydration Solutions

Two-Dimensional Separation of Protein Samples

This page describes two-dimensional separation of protein samples with GE Healthcare products.

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