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G3295

Sigma-Aldrich

GW0742

≥98% (HPLC)

Sinonimo/i:

4-[2-(3-Fluoro-4-trifluoromethyl-phenyl)-4-methyl-thiazol-5-ylmethylsulfanyl]- 2-methyl-phenoxy}-acetic acid

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About This Item

Formula empirica (notazione di Hill):
C21H17F4NO3S2
Numero CAS:
317318-84-6
Peso molecolare:
471.49
Numero MDL:
MFCD07369423
Codice UNSPSC:
12352200
ID PubChem:
24895123
NACRES:
NA.77

Saggio

≥98% (HPLC)

Forma fisica

powder

Colore

white

Punto di fusione

134.5-135.5 °C

Solubilità

DMSO: >5 mg/mL
H2O: insoluble

Ideatore

GlaxoSmithKline

Temperatura di conservazione

2-8°C

Stringa SMILE

Cc1cc(SCc2sc(nc2C)-c3ccc(c(F)c3)C(F)(F)F)ccc1OCC(O)=O

InChI

1S/C21H17F4NO3S2/c1-11-7-14(4-6-17(11)29-9-19(27)28)30-10-18-12(2)26-20(31-18)13-3-5-15(16(22)8-13)21(23,24)25/h3-8H,9-10H2,1-2H3,(H,27,28)
HWVNEWGKWRGSRK-UHFFFAOYSA-N

Informazioni sul gene

human ... PPARA(5465) , PPARD(5467) , PPARG(5468)

Azioni biochim/fisiol

GW0742 is a highly selective PPARδ agonist. EC50 = 1 nM vs 1 μM and 2 μM for PPARα and PPARγ, respectively.

Caratteristiche e vantaggi

This compound is featured on the Nuclear Receptors (PPARs) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
This compound was developed by GlaxoSmithKline. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Note legali

Sold for research purposes under agreement from Glaxo­Smith­Kline

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

Eyeshields, Gloves, type N95 (US)

Certificati d'analisi (COA)

Cerca il Certificati d'analisi (COA) digitando il numero di lotto/batch corrispondente. I numeri di lotto o di batch sono stampati sull'etichetta dei prodotti dopo la parola ‘Lotto’ o ‘Batch’.

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