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Merck
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Key Documents

Altri documenti

F1016

Sigma-Aldrich

Fenoterol hydrobromide

Sinonimo/i:

2-(3,5-Dihydroxyphenyl)-2-hydroxy-2′-(4-hydroxyphenyl)-1′-methyldiethylamine hydrobromide

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About This Item

Formula empirica (notazione di Hill):
C17H21NO4 · HBr
Numero CAS:
1944-12-3
Peso molecolare:
384.26
Numero CE:
217-742-8
Numero MDL:
MFCD00079288
Codice UNSPSC:
12352200
ID PubChem:
24278431
NACRES:
NA.77

Livello qualitativo

100

Ideatore

Boehringer Ingelheim

Stringa SMILE

Br[H].CC(Cc1ccc(O)cc1)NCC(O)c2cc(O)cc(O)c2

InChI

1S/C17H21NO4.BrH/c1-11(6-12-2-4-14(19)5-3-12)18-10-17(22)13-7-15(20)9-16(21)8-13;/h2-5,7-9,11,17-22H,6,10H2,1H3;1H
SGZRQMALQBXAIQ-UHFFFAOYSA-N

Informazioni sul gene

human ... ADRB2(154)

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Descrizione generale

Fenoterol hydrobromide is a sympathomimetic drug. It is used to treat asthma, bronchitis and emphysema. Fenoterol administration might be linked to liver damage. It has anti-inflammatory effects on eosinophil function.

Applicazioni

Fenoterol hydrobromide has been used in chromatography-tandem mass spectrometry (LC&-MS-MS) for specific and sensitive detection of β-agonists (BAG).

Azioni biochim/fisiol

β2-adrenoceptor agonist; bronchodilator.

Caratteristiche e vantaggi

This compound was developed by Boehringer Ingelheim. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Applicazioni

N° Catalogo
Descrizione
Determinazione del prezzo

Pittogrammi

Exclamation mark
GHS07

Avvertenze

Warning

Indicazioni di pericolo

H302

Consigli di prudenza

P301 + P312 + P330

Classi di pericolo

Acute Tox. 4 Oral

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Dispositivi di protezione individuale

dust mask type N95 (US), Eyeshields, Gloves

Certificati d'analisi (COA)

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Forskolina

Krzysztof Jozwiak et al.
Chirality, 23 Suppl 1, E1-E6 (2011-05-28)
The β(2) adrenergic receptor (β(2)-AR) is a model system for studying the ligand recognition process in G protein-coupled receptors. Fenoterol (FEN) is a β(2)-AR selective agonist that has two centers of chirality and exists as four stereoisomers. Radioligand binding studies
Hegui Wang et al.
PloS one, 7(9), e46186-e46186 (2012-10-03)
Increasing evidence indicates that the rapid component of delayed rectifier potassium current (I(Kr)) is modulated by α- and β-adrenergic stimulation. However, the role and mechanism regulating I(Kr) through β(2)-adrenoreceptor (β-AR) stimulation in heart failure (HF) are unclear. In the present
Joanne Chung Yan Yeung et al.
Analytica chimica acta, 742, 37-44 (2012-08-14)
In vivo solid-phase microextraction (SPME) can be used to sample the circulating blood of animals without the need to withdraw a representative blood sample. In this study, in vivo SPME in combination with liquid-chromatography tandem mass spectrometry (LC-MS/MS) was used
T Katsunuma et al.
American journal of respiratory cell and molecular biology, 21(3), 409-417 (1999-08-26)
Neurokinin A (NKA) induces bronchoconstriction mediated by tachykinin NK(2) receptors in animals and humans, and may be increased in asthma. Because beta(2)-adrenoceptor agonists are the most widely used bronchodilators in asthma, we investigated the effects of the beta(2)-adrenoceptor agonist fenoterol
Ka-Pan Lam et al.
Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology, 22(4), 431-439 (2011-02-16)
Short-acting β2-adrenoreceptor agonist (SABA) is the major asthma reliever as indicated in the GINA guidelines. Regulated on activation, normal T expressed and secreted (RANTES) is a chemokine that attracts eosinophils, mast cells, and basophils toward site of allergic inflammation. Interferon
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Chromatograms

application for HPLC

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