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S8260

Sigma-Aldrich

Salbutamol

≥96% (GC), powder, β2 adrenoceptor agonist

Sinonimo/i:

α-[(tert-Butylamino)methyl]-4-hydroxy-m-xylene-α,α′-diol, Albuterol

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About This Item

Formula empirica (notazione di Hill):
C13H21NO3
Numero CAS:
18559-94-9
Peso molecolare:
239.31
Beilstein:
6405698
Numero CE:
242-424-0
Numero MDL:
MFCD00148978
Codice UNSPSC:
12352200
ID PubChem:
24278712
NACRES:
NA.77

product name

Salbutamol,

Livello qualitativo

100

Solubilità

methanol: complete 50 mg/ml, clear, colorless to yellow

Ideatore

GlaxoSmithKline

Stringa SMILE

CC(C)(C)NCC(O)c1ccc(O)c(CO)c1

InChI

1S/C13H21NO3/c1-13(2,3)14-7-12(17)9-4-5-11(16)10(6-9)8-15/h4-6,12,14-17H,7-8H2,1-3H3
NDAUXUAQIAJITI-UHFFFAOYSA-N

Informazioni sul gene

human ... ADRB2(154)

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Applicazioni

Salbutamol was administered to primate model to study the bronchoconstriction in chronic allergic asthma.20 Salbutamol was used as a standard for rapid pharmacokinetic screening of human plasma samples using HPLC.21

Azioni biochim/fisiol

Salbutamol is a β2 adrenoceptor agonist with short acting bronchodilation and anti-inflammatory effects. It relaxes the airway smooth muscles and inhibits bronchoconstriction induced by adenosine-5′ -monophosphate (AMP).1 Salbutamol is particularly effective in treatment of asthma as it provides immediate relief.2
β2-adrenoceptor agonist

Caratteristiche e vantaggi

This compound is featured on the β-Adrenoceptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
This compound was developed by GlaxoSmithKline. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Applicazioni

N° Catalogo
Descrizione
Determinazione del prezzo

Pittogrammi

Exclamation mark
GHS07

Avvertenze

Warning

Indicazioni di pericolo

H302,H317,H319,H412

Classi di pericolo

Acute Tox. 4 Oral - Aquatic Chronic 3 - Eye Irrit. 2 - Skin Sens. 1B

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 2

Dispositivi di protezione individuale

dust mask type N95 (US), Eyeshields, Gloves

Certificati d'analisi (COA)

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Chromatograms

application for HPLC

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