C4680

α-Cyclodextrin

powder, BioReagent, suitable for cell culture, ≥98%

• Sinonimo/i: α-Schardinger dextrin, Cyclohexaamylose, Cyclomaltohexaose
• Formula empirica (notazione di Hill): C₃₆H₆₀O₃₀
• Numero CAS: 10016-20-3
• Peso molecolare: 972.84
• Beilstein: 79627
• Numero CE: 233-007-4
• Numero MDL: MFCD00078207
• Codice UNSPSC: 12352201
• ID PubChem: 24892712
• NACRES: NA.77

Proprietà

• Sterilità: non-sterile
• Livello qualitativo: 200
• Nome Commerciale: BioReagent
• Saggio: ≥98%
• Stato: powder
• tecniche: cell culture | mammalian: suitable
• Punto di fusione: >278 °C (dec.) (lit.)
• Solubilità: H₂O: 10 mg/mL
• Condizioni di spedizione: ambient
• Temperatura di conservazione: room temp
• Stringa SMILE: OC[C@H]1O[C@@H]2O[C@H]3[C@H](O)[C@@H](O)[C@H](O[C@@H]3CO)O[C@H]4[C@H](O)[C@@H](O)[C@H](O[C@@H]4CO)O[C@H]5[C@H](O)[C@@H](O)[C@H](O[C@@H]5CO)O[C@H]6[C@H](O)[C@@H](O)[C@H](O[C@@H]6CO)O[C@H]7[C@H](O)[C@@H](O)[C@H](O[C@@H]7CO)O[C@H]1[C@H](O)[C@H]2O
• InChI: 1S/C36H60O30/c37-1-7-25-13(43)19(49)31(55-7)62-26-8(2-38)57-33(21(51)15(26)45)64-28-10(4-40)59-35(23(53)17(28)47)66-30-12(6-42)60-36(24(54)18(30)48)65-29-11(5-41)58-34(22(52)16(29)46)63-27-9(3-39)56-32(61-25)20(50)14(27)44/h7-54H,1-6H2/t7-,8-,9-,10-,11-,12-,13-,14-,15-,16-,17-,18-,19-,20-,21-,22-,23-,24-,25-,26-,27-,28-,29-,30-,31-,32-,33-,34-,35-,36-/m1/s1; HFHDHCJBZVLPGP-RWMJIURBSA-N

Descrizione

Descrizione generale

α-Cyclodextrin (α-CD) is a cyclic oligosaccharide that consists of six glucopyranose units linked by α-(1,4) bonds. α-CD acts as a soluble dietary fiber and hence it is preferred to be widely used in food industry.

Applicazioni

Useful for the solubilization of nonpolar macromolecules such as fatty acids, lipids, and cholesterol for use in cell culture applications. α-Cyclodextrin has been used to solubilize odanacatib, a cathepsin K inhibitor.

Azioni biochim/fisiol

α-Cyclodextrin is found to form a firm complex with dietary fats. This way it decreases the bioavailability and absorption of fats. It is known to regulate triglyceride and leptin levels in serum. In rat models, α-Cyclodextrin is shown to induce insulin sensitivity and fecal fat excretion. Thus, α-cyclodextrin is considered to be effective for treating obesity and metabolic syndromes.

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 11 - Combustible Solids
• Classe di pericolosità dell'acqua (WGK): WGK 1
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable
• Dispositivi di protezione individuale: Eyeshields, Gloves, type N95 (US)