C4407
Human Collagen Type III
from human placenta, powder, suitable for cell culture
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About This Item
Prodotti consigliati
product name
Collagene, Bornstein and Traub Type III (Sigma Type X), powder
Origine biologica
human placenta
Livello qualitativo
Saggio
≥90% (GE)
Forma fisica
powder
tecniche
cell culture | mammalian: suitable
Impurezze
HIV, hepatitis B and hepatitis C, none detected
Solubilità
aqueous acid: soluble
N° accesso UniProt
Temperatura di conservazione
2-8°C
Informazioni sul gene
human ... COL3A1(1300)
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Applicazioni
Collagen from human placenta has been used to assess the bioelectric effects of quinine on airway epithelial cells, to study the selective toxicity of engineered lentvirus lytic peptides and in a particle aggregation assay for the rapid detection of fibronectin, fibrinogen and collagen receptors on Staphylococcus aureus. It has also been used in a magnesium-dependent, collagen-binding assay during characterization of human lung tumor-associated antigens.
Componenti
All collagen molecules are composed of three polypeptide chains arranged in a triple helical conformation, with a primary structure that is mostly a repeating motif with glycine in every third position and proline or 4-hydroxyproline frequently preceding the glycine residue.
Avvertenza
This product should be stored at 2-8 °C and will retain activity in these conditions for 2 years.
Nota sulla preparazione
This product was prepared by a modification of the pepsin extraction and salt fractionation method of Hill, R.J. and Harper, E., Anal. Biochem., 141 (1984). It is a lyophilized powder that can be reconstituted in sterile .5 M acetic acid, PBS or water at 1 mg/mL. A PBS solution will be stable for at least one year at -20°C.
Risultati analitici
An SDS polyacrylamide gel electrophoresis test run under reducing conditions consistent with basement membrane collagen yields three major bands.
Altre note
Il collagene è classificato in diversi tipi strutturalmente e geneticamente distinti. Sigma utilizza la nomenclatura proposta da Bornstein e Traub. Occorre prestare attenzione a non confondere le denominazioni delle tipologie Sigma con le classificazioni del collagene universalmente riconosciute.
Codice della classe di stoccaggio
11 - Combustible Solids
Classe di pericolosità dell'acqua (WGK)
WGK 1
Punto d’infiammabilità (°F)
Not applicable
Punto d’infiammabilità (°C)
Not applicable
Dispositivi di protezione individuale
Eyeshields, Gloves, type N95 (US)
Certificati d'analisi (COA)
Cerca il Certificati d'analisi (COA) digitando il numero di lotto/batch corrispondente. I numeri di lotto o di batch sono stampati sull'etichetta dei prodotti dopo la parola ‘Lotto’ o ‘Batch’.
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