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PHR1666

Supelco

Dietiletere

Pharmaceutical Secondary Standard; Certified Reference Material

Sinonimo/i:

Etere, Etil etere

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About This Item

Formula condensata:
(CH3CH2)2O
Numero CAS:
Peso molecolare:
74.12
Beilstein:
1696894
Numero CE:
Numero MDL:
Codice UNSPSC:
41116107
ID PubChem:
NACRES:
NA.24

Grado

certified reference material
pharmaceutical secondary standard

Livello qualitativo

Densità del vapore

2.6 (vs air)

CdA

current certificate can be downloaded

Temp. autoaccensione

320 °F

Qualità

pharmaceutical secondary standard

Limite di esplosione

36.5 %

Confezionamento

pkg of 3 × 1.2 mL

tecniche

HPLC: suitable
gas chromatography (GC): suitable

Indice di rifrazione

n20/D 1.3530 (lit.)

P. eboll.

34.6 °C (lit.)

Punto di fusione

−116 °C (lit.)

Densità

0.706 g/mL at 25 °C (lit.)

applicazioni

pharmaceutical (small molecule)

Formato

neat

Temperatura di conservazione

2-30°C

Stringa SMILE

CCOCC

InChI

1S/C4H10O/c1-3-5-4-2/h3-4H2,1-2H3
RTZKZFJDLAIYFH-UHFFFAOYSA-N

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Descrizione generale

Diethyl ether is a non-polar volatile organic solvent, commonly used as an extraction solvent in liquid-liquid extraction for separation of post reaction residues from synthetic products.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Applicazioni

Diethyl ether may be used as a solvent reference standard for the determination of the analyte in bulk drug and pharmaceutical formulations by gas chromatography.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Altre note

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Nota a piè di pagina

To see an example of a Certificate of Analysis for this material enter LRAC0145 in the slot below. This is an example certificate only and may not be the lot that you receive.

Prodotti consigliati

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

Pittogrammi

FlameExclamation mark

Avvertenze

Danger

Indicazioni di pericolo

Classi di pericolo

Acute Tox. 4 Oral - Flam. Liq. 1 - STOT SE 3

Organi bersaglio

Central nervous system

Rischi supp

Codice della classe di stoccaggio

3 - Flammable liquids

Classe di pericolosità dell'acqua (WGK)

WGK 1

Punto d’infiammabilità (°F)

-40.0 °F - closed cup

Punto d’infiammabilità (°C)

-40 °C - closed cup


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Certificati d'analisi (COA)

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Dietiletere puriss., contains ~5 mg/L 2,6-di-tert.-butyl-4-methylphenol as stabilizer, meets analytical specification of Ph. Eur., BP, ≥99.5% (GC)

Sigma-Aldrich

24004

Dietiletere

Dietiletere reagent grade, ≥98%, contains ≤2% ethanol and ≤10ppm BHT as inhibitor

Sigma-Aldrich

346144

Dietiletere

Dietiletere suitable for HPLC, ≥99.9%, inhibitor-free

Sigma-Aldrich

309966

Dietiletere

Dietiletere contains 1 ppm BHT as inhibitor, anhydrous, ≥99.7%

Sigma-Aldrich

296082

Dietiletere

Residual solvent testing: a review of gas-chromatographic and alternative techniques
B'Hymer C
Pharmaceutical Research, 20(3), 337-344 (2003)
Determination of residual solvent levels in bulk pharmaceuticals by capillary gas chromatography
Smith ID and Waters DG
Analyst, 116(12), 1327-1331 (1991)
Organic solvents in the pharmaceutical industry
Grodowska K and Parczewski A
Acta Poloniae Pharmaceutica, 67(1), 3-12 (2010)

Protocolli

GC Analysis of Class 3 Residual Solvents on SUPELCOWAX® 10

Contenuto correlato

Butyl methyl ether; Acetic acid; 2-Butanone; Ethyl acetate; Tetrahydrofuran; 1-Butanol; Isopropyl acetate; Heptane; Propyl acetate; 3-Methylbutanol; 4-Methyl-2-pentanone; Isobutyl acetate; Butyl acetate; Dimethyl sulfoxide; Anisole; Cumene

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