C1484

7-Diethylamino-3-(4-maleimidophenyl)-4-methylcoumarin

≥95% purity (HPLC), solid

• Sinonimo/i: 1H-Pyrrole-2,5-dione, 1-(4-(7-(diethylamino)-4-methyl-2-oxo-2H-1-benzopyran-3-yl)phenyl)-, CPM
• Formula empirica (notazione di Hill): C₂₄H₂₂N₂O₄
• Numero CAS: 76877-33-3
• Peso molecolare: 402.44
• Numero MDL: MFCD00077334
• Codice UNSPSC: 12171500
• ID PubChem: 24892413
• NACRES: NA.47

Proprietà

• product name: 7-Diethylamino-3-(4-maleimidophenyl)-4-methylcoumarin, ≥95% (HPLC), solid
• Livello qualitativo: 100
• Saggio: ≥95% (HPLC)
• Forma fisica: solid
• Colore: yellow
• Solubilità: DMSO: soluble; methanol: soluble
• applicazioni: diagnostic assay manufacturing; hematology; histology
• Temperatura di conservazione: −20°C
• Stringa SMILE: CCN(CC)c1ccc2C(C)=C(C(=O)Oc2c1)c3ccc(cc3)N4C(=O)C=CC4=O
• InChI: 1S/C24H22N2O4/c1-4-25(5-2)18-10-11-19-15(3)23(24(29)30-20(19)14-18)16-6-8-17(9-7-16)26-21(27)12-13-22(26)28/h6-14H,4-5H2,1-3H3; YGIABALXNBVHBX-UHFFFAOYSA-N

Descrizione

Descrizione generale

7-Diethylamino-3-(4-maleimidophenyl)-4-methylcoumarin (CPM), is a highly fluorescent, sulfhydryl (-SH) group containing coumarin derivative. It has excitation an emission wavelengths of 355 and 460 nm, respectively.

Applicazioni

7-Diethylamino-3-(4-maleimidophenyl)-4-methylcoumarin has been used:

• as a nontoxic substitute for conjugation with antibody(93)
• to aid fluorescent detection of Coenzyme A (CoA-SH) in human N-myristoyltransferases assay (94)
• in thermostability shift assay of recombinant protein(95)

Azioni biochim/fisiol

Used to monitor release of thiols, quantitate thiol in microplate reactions, and to distinguish proliferating cancer cells by nucleolar protein staining.

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 11 - Combustible Solids
• Classe di pericolosità dell'acqua (WGK): WGK 3
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable
• Dispositivi di protezione individuale: Eyeshields, Gloves, type N95 (US)