938963

Potassium tert-butoxide ChemBeads

• Sinonimo/i: Potassium tert-butylate, Potassium t-butoxide
• Formula empirica (notazione di Hill): KOC₄H₉
• Numero CAS: 865-47-4
• Peso molecolare: 112.21
• Numero MDL: MFCD00012162
• Codice UNSPSC: 12352100

Proprietà

• Descrizione: Reagent Type-Organic Salt
• Livello qualitativo: 100
• Stato: solid
• Composizione: wt% loading of base, 14-16 wt. %
• Impiego in reazioni chimiche: core: potassium
• Stringa SMILE: [K+].CC(C)(C)[O-]
• InChI: 1S/C4H9O.K/c1-4(2,3)5;/h1-3H3;/q-1;+1; LPNYRYFBWFDTMA-UHFFFAOYSA-N

Descrizione

Descrizione generale

Potassium tert-butoxide is a strong alkoxide base, it can deprotonate carbon and other Brφnsted acids. It is a relatively poor nucleophile.

Applicazioni

Potassium tert-butoxide has been used as a strong base in the enantioselective synthesis of amines by transfer hydrogenation of N-(tertbutylsulfinyl)imines. It can also be used: To synthesize aliphatic and aromatic amides from corresponding esters and amines. As a base in the intramolecular cyclization of aryl ethers, amines, and amides. As a catalyst to prepare styrene derivatives from aryl halides and alkenes by Mizoroki-Heck reaction.
For general uses, product is also available in powdered form (156671)

Caratteristiche e vantaggi

ChemBeads are chemical coated glass beads. ChemBeads offer improved flowability and chemical uniformity perfect for automated solid dispensing and high-throughput experimentation. The method of creating ChemBeads uses no other chemicals or surfactants allowing the user to accurately dispense sub-milligram amounts of chemical.

Altre note

High-Throughput Reaction Screening with Nanomoles of Solid Reagents Coated on Glass Beads

Versatile Methods to Dispense Sub-Milligram Quantities of Solids using Chemical Coated Beads for High-Throughput Experimentation

ChemBead Enabled High-Throughput Cross-Electrophile Coupling Reveals a New Complementary Ligand

Informazioni sulla sicurezza

• Pittogrammi: GHS02,GHS05
• Avvertenze: Danger
• Indicazioni di pericolo: H228,H252,H314
• Consigli di prudenza: P210 - P235 - P260 - P280 - P303 + P361 + P353 - P305 + P351 + P338
• Classi di pericolo: Eye Dam. 1 - Flam. Sol. 1 - Self-heat. 2 - Skin Corr. 1A
• Rischi supp: EUH014
• Codice della classe di stoccaggio: 4.2 - Pyrophoric and self-heating hazardous materials
• Classe di pericolosità dell'acqua (WGK): WGK 3