939048

Lithium bis(trimethylsilyl)amide ChemBeads

• Sinonimo/i: Hexamethyldisilazane lithium salt ChemBeads
• Formula empirica (notazione di Hill): LiC₆H₁₈NSi₂
• Peso molecolare: 167.33
• Codice UNSPSC: 12352100

Proprietà

• Descrizione: Organic Salt
• Livello qualitativo: 100
• Forma fisica: solid
• Composizione: 14-16 wt% loading of base
• Impiego in reazioni chimiche: core: lithium
• Stringa SMILE: [Li]N([Si](C)(C)C)[Si](C)(C)C
• InChI: 1S/C6H18NSi2.Li/c1-8(2,3)7-9(4,5)6;/h1-6H3;/q-1;+1; YNESATAKKCNGOF-UHFFFAOYSA-N

Descrizione

Descrizione generale

Lithium bis(trimethylsilyl)amide is a non-nucleophilic strong Brønsted base, which is generally soluble in most of the nonpolar organic solvents. It is most commonly employed in organic reactions.

Applicazioni

Base employed in generating enolates for the preparation of lactone precursors, pyranones, and cyclohexanes. Used to catalyze the addition of phosphine P-H bonds to carbodiimides leading to phosphaguanidines.[6] Also used in a novel three-step synthesis of disubstituted 1,2,5-thiadiazoles. For general uses, product is also available in powdered form (324620)

Caratteristiche e vantaggi

ChemBeads are chemical coated glass beads. ChemBeads offer improved flowability and chemical uniformity perfect for automated solid dispensing and high-throughput experimentation. The method of creating ChemBeads uses no other chemicals or surfactants allowing the user to accurately dispense sub-milligram amounts of chemical.

Altre note

• High-Throughput Reaction Screening with Nanomoles of Solid Reagents Coated on Glass Beads
• Versatile Methods to Dispense Sub-Milligram Quantities of Solids using Chemical Coated Beads for High-Throughout Experimentation
• ChemBead Enabled High-Throughput Cross-Electrophile Coupling Reveals a New Complementary Ligand

Informazioni sulla sicurezza

• Pittogrammi: GHS02,GHS05
• Avvertenze: Danger
• Indicazioni di pericolo: H228,H251,H314
• Consigli di prudenza: P210 - P235 - P260 - P280 - P303 + P361 + P353 - P305 + P351 + P338
• Classi di pericolo: Eye Dam. 1 - Flam. Sol. 1 - Self-heat. 1 - Skin Corr. 1B
• Rischi supp: EUH014
• Codice della classe di stoccaggio: 4.2 - Pyrophoric and self-heating hazardous materials
• Classe di pericolosità dell'acqua (WGK): WGK 3
• Punto d’infiammabilità (°F): 62.6 °F - closed cup
• Punto d’infiammabilità (°C): 17 °C - closed cup