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62248

Supelco

2-[4-(1-Hydroxy-2-methylpropyl)phenyl]propanoic acid

pharmaceutical impurity standard

Sinonimo/i:

1-Hydroxyibuprofen, Ibuprofen impurity L (PhEur), 2-[4-(1-Hydroxy-2-methylpropyl)phenyl]propionic acid

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About This Item

Formula empirica (notazione di Hill):
C13H18O3
Numero CAS:
53949-53-4
Peso molecolare:
222.28
Beilstein:
22307543
Numero MDL:
MFCD08275586
Codice UNSPSC:
41116107
ID PubChem:
329759723
NACRES:
NA.24

Livello qualitativo

100

Saggio

≥98.0% (HPLC)

Durata

limited shelf life, expiry date on the label

Impurezze

≤0.5% water

applicazioni

forensics and toxicology
pharmaceutical (small molecule)

Formato

neat

Stringa SMILE

CC(C)C(O)c1ccc(cc1)C(C)C(O)=O

InChI

1S/C13H18O3/c1-8(2)12(14)11-6-4-10(5-7-11)9(3)13(15)16/h4-9,12,14H,1-3H3,(H,15,16)
RMOQYHYFRKTDRI-UHFFFAOYSA-N

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Pittogrammi

Exclamation mark
GHS07

Avvertenze

Warning

Indicazioni di pericolo

H302

Consigli di prudenza

P301 + P312 + P330

Classi di pericolo

Acute Tox. 4 Oral

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

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Certificati d'analisi (COA)

Lot/Batch Number
BCCD7873
BCCD4481
BCCC6554
BCCB5695
BCBV2399

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Ibuprofene ≥98% (GC)

Sigma-Aldrich

I4883

Ibuprofene

Chloé S Baron et al.
Cell, 179(2), 527-542 (2019-10-05)
Much of current molecular and cell biology research relies on the ability to purify cell types by fluorescence-activated cell sorting (FACS). FACS typically relies on the ability to label cell types of interest with antibodies or fluorescent transgenic constructs. However
Chi-Yeh Chung et al.
Cell reports, 29(2), 495-510 (2019-10-10)
Technological improvements enable single-cell epigenetic analyses of organ development. We reasoned that high-resolution single-cell chromatin accessibility mapping would provide needed insight into the epigenetic reprogramming and transcriptional regulators involved in normal mammary gland development. Here, we provide a single-cell resource
Dobeen Hwang et al.
Cell chemical biology, 26(9), 1229-1239 (2019-06-25)
Homogeneous antibody-drug conjugates (ADCs) that use a highly reactive buried lysine (Lys) residue embedded in a dual variable domain (DVD)-IgG1 format can be assembled with high precision and efficiency under mild conditions. Here we show that replacing the Lys with
Tanner O Monroe et al.
Developmental cell, 48(6), 765-779 (2019-02-19)
Specialized adult somatic cells, such as cardiomyocytes (CMs), are highly differentiated with poor renewal capacity, an integral reason underlying organ failure in disease and aging. Among the least renewable cells in the human body, CMs renew approximately 1% annually. Consistent
Kamila Burdova et al.
The EMBO journal, 38(20), e101443-e101443 (2019-08-20)
Cyclins are central engines of cell cycle progression in conjunction with cyclin-dependent kinases (CDKs). Among the different cyclins controlling cell cycle progression, cyclin F does not partner with a CDK, but instead forms via its F-box domain an SCF (Skp1-Cul1-F-box)-type
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