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Merck
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Key Documents

Altri documenti

30122

Sigma-Aldrich

L-cisteina

tested according to Ph. Eur.

Sinonimo/i:

Cysteini hydrochloridum monohydricum

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About This Item

Formula condensata:
HSCH2CH(NH2)COOH · HCl · H2O
Numero CAS:
7048-04-6
Peso molecolare:
175.63
Beilstein:
5158059
Numero CE:
200-157-7
Numero MDL:
MFCD00065606
Codice UNSPSC:
12352209
eCl@ss:
32160406
ID PubChem:
329753438

agenzia

USP/NF
tested according to Ph. Eur.

Livello qualitativo

100

Saggio

98.5-101.0%

Forma fisica

solid

Punto di fusione

176 °C

Solubilità

H2O: soluble 100 g/L at 25 °C

applicazioni

pharmaceutical (small molecule)

Stringa SMILE

O.Cl.N[C@@H](CS)C(O)=O

InChI

1S/C3H7NO2S.ClH.H2O/c4-2(1-7)3(5)6;;/h2,7H,1,4H2,(H,5,6);1H;1H2/t2-;;/m0../s1
QIJRTFXNRTXDIP-JIZZDEOASA-N

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Categorie correlate

Applicazioni

L-Cysteine hydrochloride monohydrate was used in the synthesis of polycarbophil-cysteine conjugate.

Azioni biochim/fisiol

Cysteine is a non-essential, thiol-containing amino acid that has protective effects in normal tissues. It is converted to glutathione that decreases the effects of chemotherapeutic and radiation agents. This might restrict the effect of therapeutic agents used for cancer treatment.
Antagonista del recettore glutammatergico NMDA.

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 1

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

dust mask type N95 (US), Eyeshields, Gloves

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Certificati d'analisi (COA)

Lot/Batch Number
BCBL3252V
BCBK6080V
BCBK4297V
BCBJ4111V
BCBH2069V

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J C Roberts
Amino acids, 8(2), 113-124 (1995-06-01)
The thiol-containing amino acid, cysteine, and its analogs are useful for a variety of protective applications, including protecting normal tissues against the unwanted side effects of cancer chemotherapeutic agents and radiation treatment. The protection can result from both direct action
M K Marschütz et al.
Pharmaceutical research, 17(12), 1468-1474 (2001-04-17)
To develop an oral controlled release system for insulin. The polymer-inhibitor conjugates carboxymethylcellulose (CMC)-Bowman-Birk inhibitor and CMC-elastatinal were homogenized with polycarbophil-cysteine conjugate, insulin, and mannitol, compressed to 2 mg microtablets and enteric coated with a polymethacrylate. The protective effect of
Matthew Oser et al.
Journal of cell science, 123(Pt 21), 3662-3673 (2010-10-26)
Invadopodia are matrix-degrading membrane protrusions in invasive carcinoma cells enriched in proteins that regulate actin polymerization. The on-off regulatory switch that initiates actin polymerization in invadopodia requires phosphorylation of tyrosine residues 421, 466, and 482 on cortactin. However, it is
Qinjian Zhao et al.
Human vaccines & immunotherapeutics, 10(3), 734-739 (2013-12-05)
Cryo-transmission electron microscopy (cryoTEM) is a powerful characterization method for assessing the structural properties of biopharmaceutical nanoparticles, including Virus Like Particle-based vaccines. We demonstrate the method using the Human Papilloma Virus (HPV) VLPs in GARDASIL®. CryoTEM, coupled to automated data
Jiahua Li et al.
American journal of physiology. Cell physiology, 305(2), C190-C196 (2013-05-17)
Claudins constitute a family of tight junction transmembrane proteins whose first extracellular loop (ECL1) determines the paracellular permeability and ion selectivity in epithelia. There are two cysteines in the ECL1 that are conserved among all claudins. We hypothesized that these
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