MATRESIQUIM0D

Resiquimod Non-Endotoxin Pyrogen (NEP) Control

for use with PyroMAT^®

• Sinonimo/i: Imidazoquinolinon
• Codice UNSPSC: 41116129
• NACRES: NA.74

Proprietà

• agenzia: EP; JP 4.06; USP
• Livello qualitativo: 400
• Stato: lyophilized
• Produttore/marchio commerciale: PyroMAT^®
• applicazioni: pharmaceutical; pyrogen testing
• Compatibilità: for use with PyroMAT^®; pyrogenic bacteria
• Condizioni di spedizione: ambient
• Temperatura di conservazione: −20°C

Descrizione

Descrizione generale

Resiquimod is a non-endotoxin pyrogen which will serve as a positive control during pyrogen testing with PyroMAT^® system.Non- Endotoxin Pyrogen (NEP) Control Resiquimod is an imidazoquinolinone compound possessing a potent anti-viral activity, supplied in a lyophilized form. It is designed to mimic the NEPs of viral origin. Resiquimod Non- Endotoxin Pyrogen (NEP) Control activates TLR7/TLR8 receptor of monocytes and is used as a positive control for PyroMAT^® system. The response to pyrogenic substances is determined by measuring the Interleukin-6 (IL-6) produced by the monocytes using ELISA microplate.

Applicazioni

Resiquimod Non- Endotoxin Pyrogen (NEP) Control can be used as a positive control with the PyroMAT^® System. It is to be used for Product Specific Validation (PSV) and routine testing to show that the system can detect non-endotoxin pyrogen contaminants in pharmaceutical products.

Note legali

PYROMAT is a registered trademark of Merck KGaA, Darmstadt, Germany

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 11 - Combustible Solids
• Classe di pericolosità dell'acqua (WGK): WGK 3
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable