M-132

N-metil-N-(trimetilsilil)trifluoroacetammide

ampule of 10 × 1.2 mL, analytical standard, Cerilliant^®

• Sinonimo/i: N-trimetilsililN-metil trifluoroacetammide, MSTFA
• Formula condensata: CF₃CON(CH₃)Si(CH₃)₃
• Numero CAS: 24589-78-4
• Peso molecolare: 199.25
• Beilstein: 1941550
• Numero CE: 246-331-6
• Numero MDL: MFCD00000411
• Codice UNSPSC: 41116107
• ID PubChem: 329817869
• NACRES: NA.24

Proprietà

• Grado: analytical standard
• Livello qualitativo: 100
• Densità del vapore: >1 (vs air)
• Tensione di vapore: 8.8 mmHg ( 27 °C)
• Impiego in reazioni chimiche: reagent type: derivatization reagent; reaction type: Acylations
• Confezionamento: ampule of 10 × 1.2 mL
• Produttore/marchio commerciale: Cerilliant^®
• tecniche: gas chromatography (GC): suitable
• Indice di rifrazione: n20/D 1.38 (lit.)
• P. ebollizione: 130-132 °C (lit.)
• Densità: 1.075 g/mL at 25 °C (lit.)
• applicazioni: forensics and toxicology
• Formato: neat
• Temperatura di conservazione: −20°C
• Stringa SMILE: CN(C(=O)C(F)(F)F)[Si](C)(C)C
• InChI: 1S/C6H12F3NOSi/c1-10(12(2,3)4)5(11)6(7,8)9/h1-4H3; MSPCIZMDDUQPGJ-UHFFFAOYSA-N

Descrizione

Descrizione generale

MSTFA (N-Methyl-N-trimethylsilylfluoroacetamide) is an important trimethylsilyl reagent, and a commonly applied reagent since it is highly reactive towards a broad range of compound classes. GC-MS optimization studies reveal the use of this reagent either alone or in combination with 1% of trimethylchlorosilane as a catalyst for silylation of complex mixtures. It has similar reactivity as BSA and BSTFA.

Applicazioni

MSTFA reagent may be used as a derivatizing agent in the following:

• Analysis of estrogen steroids such as estrone (E1), 17α-ethinylestradiol (EE2), and trenbolone acetate metabolites, melengestrol in environmental matrices using gas chromatography coupled to mass spectrometry (GC-MS).
• Quantification of ibuprofen, naproxen, ketoprofen, and diclofenac in wastewater samples using gas chromatography coupled to mass spectrometry (GC-MS).

Caratteristiche e vantaggi

• Very volatile of TMS-acetamides.
• More volatile than BSA or BSTFA but with similar silylation strength.
• Useful in the analysis of volatile trace materials.
• Used in the preparation of volatile and thermally stable derivatives for GC and MS analysis.

Note legali

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany

Informazioni sulla sicurezza

• Pittogrammi: GHS02,GHS07
• Avvertenze: Warning
• Indicazioni di pericolo: H226,H315,H319,H335
• Consigli di prudenza: P210 - P302 + P352 - P305 + P351 + P338
• Classi di pericolo: Eye Irrit. 2 - Flam. Liq. 3 - Skin Irrit. 2 - STOT SE 3
• Organi bersaglio: Respiratory system
• Codice della classe di stoccaggio: 3 - Flammable liquids
• Classe di pericolosità dell'acqua (WGK): WGK 3
• Punto d’infiammabilità (°F): 78.8 °F - closed cup
• Punto d’infiammabilità (°C): 26 °C - closed cup