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W224847

Sigma-Aldrich

4-Carvomenthenol

≥95%, FCC, FG

Sinonimo/i:

4-Terpinenol

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About This Item

Formula empirica (notazione di Hill):
C10H18O
Numero CAS:
562-74-3
Peso molecolare:
154.25
Numero FEMA:
2248
Numero CE:
209-235-5
N° CoE:
2229
Numero MDL:
MFCD00001562
Codice UNSPSC:
12164502
ID PubChem:
24900947
Numero Flavis:
2.072
NACRES:
NA.21

Origine biologica

synthetic

Livello qualitativo

400

Grado

FG
Halal

Conformità normativa

EU Regulation 1334/2008 & 872/2012
FCC
FDA 21 CFR 117
FDA 21 CFR 172.515

Saggio

≥95%

Indice di rifrazione

n20/D 1.478

P. eboll.

88-90 °C

Densità

0.931 g/mL at 25

applicazioni

flavors and fragrances

Documentazione

see Safety & Documentation for available documents

Allergene alimentare

no known allergens

Organolettico

woody; earthy; pepper

Stringa SMILE

CC(C)C1(O)CCC(C)=CC1

InChI

1S/C10H18O/c1-8(2)10(11)6-4-9(3)5-7-10/h4,8,11H,5-7H2,1-3H3
WRYLYDPHFGVWKC-UHFFFAOYSA-N

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Categorie correlate

Descrizione generale

Natural occurrence: Anise, basil, black currant, cocoa, coriander, cranberry, grapefruit, lemon, lime, marjoram, peppermint oil, nutmeg and spearmint.

Applicazioni

  • 4-Carvomenthenol ameliorates the murine combined allergic rhinitis and asthma syndrome by inhibiting IL-13 and mucus production via p38MAPK/NF-κB signaling pathway axis.: Demonstrates the anti-inflammatory and therapeutic potentials of 4-Carvomenthenol in treating respiratory conditions, highlighting its mechanism of action at the molecular level (Bezerra Barros et al., 2020).

Azioni biochim/fisiol

Taste at 30 ppm

Pittogrammi

Exclamation mark
GHS07

Avvertenze

Warning

Indicazioni di pericolo

H302,H315,H319,H335

Classi di pericolo

Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Organi bersaglio

Respiratory system

Codice della classe di stoccaggio

10 - Combustible liquids

Classe di pericolosità dell'acqua (WGK)

WGK 1

Dispositivi di protezione individuale

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

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Certificati d'analisi (COA)

Lot/Batch Number
SHBN7748
SHBM6369
MKCJ3542
MKCG7322
MKCF9748

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Sigma-Aldrich

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Diphenyl ether ≥99%, FG

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Sigma-Aldrich

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Sigma-Aldrich

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α-Terpineol

Antonella Casiraghi et al.
Pharmaceutical development and technology, 15(5), 545-552 (2009-10-22)
This work aimed to evaluate the effect induced by excipients conventionally used for topical dosage forms, namely isopropyl myristate (IPM) or oleic acid (OA) or polyethylene glycol 400 (PEG400) or Transcutol (TR), on the human skin permeability of terpinen-4-ol (T4OL)
Risa Haigou et al.
Journal of oleo science, 61(1), 35-43 (2011-12-23)
We examined the in vitro metabolism of (+)-terpinen-4-ol by human liver microsomes and recombinant enzymes. The biotransformation of (+)-terpinen-4-ol was investigated by gas chromatography-mass spectrometry (GC-MS). (+)-Terpinen-4-ol was found to be oxidized to (+)-(1R,2S,4S)-1,2-epoxy-p-menthan-4-ol, (+)-(1S,2R,4S)-1,2-epoxy-p-menthan-4-ol, and (4S)-p-menth-1-en-4,8-diol by human liver
Mi-Jin Park et al.
Journal of microbiology (Seoul, Korea), 48(4), 496-501 (2010-08-28)
In this study, the antibacterial activity of essential oil from Chamaecyparis obtusa (Sieb. et Zucc) leaves and twigs was investigated. The test strains were Klebsiella pneumoniae, Listeria monocytogenes, Salmonella typhimurium, Staphylococcus aureus, Escherichia coli, Legionella pneumophila, and Methicilline-resistant Staphylococcus aureus.
C Njume et al.
International journal of antimicrobial agents, 38(4), 319-324 (2011-07-15)
The aim of this study was to isolate and identify phytochemicals with anti-Helicobacter pylori activity from the stem bark of Sclerocarya birrea. The plant crude extract was fractionated by silica gel column and thin layer chromatography techniques, initially with ethyl
Kotchaphan Chooluck et al.
Planta medica, 78(16), 1761-1766 (2012-10-03)
The purpose of this study was to investigate dermal pharmacokinetics of terpinen-4-ol in rats following topical administration of plai oil derived from the rhizomes of Zingiber cassumunar Roxb. Unbound terpinen-4-ol concentrations in dermal tissue were measured by microdialysis. The dermal
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