931853

SPhos Pd G6 acylation

≥95%

• Sinonimo/i: (SPhos)Pd(4-CH₂CH₂CONHSPh)Br
• Formula empirica (notazione di Hill): C₃₉H₄₇BrNO₆PPd
• Numero CAS: 2723495-97-2
• Peso molecolare: 843.09
• Numero MDL: MFCD34704619
• Codice UNSPSC: 12352100
• NACRES: NA.21

Proprietà

• Livello qualitativo: 100
• Saggio: ≥95%
• Stato: powder
• Impiego in reazioni chimiche: reagent type: catalyst; reaction type: Cross Couplings
• Caratteristiche più verdi: Catalysis; Learn more about the Principles of Green Chemistry.
• sustainability: Greener Alternative Product
• Categoria alternativa più verde: Aligned

Descrizione

Descrizione generale

We are committed to bringing you Greener Alternative Products, which adhere to one or more of The 12 Principles of Green Chemistry. This product has been enhanced for catalytic efficiency. Click here for more information.

Applicazioni

SPhos Pd G6 acylation is an oxidative addition complex (OAC) of SPhos for use in bioconjugation. The pendant NHS-functional group allows coupling to protein amines through a selective acylation. The protein-OAC can then be reacted with a second, cysteine-containing protein. This facile approach allows for protein homodimerization as well as the formation of antibody-protein conjugates.

Learn more about G6 Buchwald precatalysts

Altre note

Palladium–Protein Oxidative Addition Complexes by Amine-Selective Acylation

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 11 - Combustible Solids
• Classe di pericolosità dell'acqua (WGK): WGK 3
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable