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257478

Sigma-Aldrich

2,2,3,3,3-Pentafluoro-1-propanol

97%

Sinonimo/i:

PFPOH

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About This Item

Formula condensata:
CF3CF2CH2OH
Numero CAS:
Peso molecolare:
150.05
Beilstein:
1743133
Numero CE:
Numero MDL:
Codice UNSPSC:
12352100
ID PubChem:
NACRES:
NA.22

Livello qualitativo

Saggio

97%

Forma fisica

liquid

Indice di rifrazione

n20/D 1.288 (lit.)

P. eboll.

80 °C/748 mmHg (lit.)

Densità

1.505 g/mL at 25 °C (lit.)

Gruppo funzionale

fluoro
hydroxyl

Stringa SMILE

OCC(F)(F)C(F)(F)F

InChI

1S/C3H3F5O/c4-2(5,1-9)3(6,7)8/h9H,1H2
PSQZJKGXDGNDFP-UHFFFAOYSA-N

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Descrizione generale

2,2,3,3,3-Pentafluoro-1-propanol is an alternative cleaning agent for chlorofluorocarbon.

Applicazioni

2,2,3,3,3-Pentafluoro-1-propanol has been used:
  • as derivatization reagent in detection of unlabeled and 15N2 -labeled L-tryptophan, L-kynurenine, serotonin and quinolinic acid in human and rat plasma by GC-MS
  • as derivatization reagent in simultaneous analysis of cocaine, cocaethylene and their possible metabolic and pyrolytic products in blood, urine and muscle by GC-MS
  • preparation of trifluoromethyl ynamines which, in turn, converted aldehydes to α-trifluoromethyl-α,β-unsaturated amides
  • to generate fluorinated α-keto ethers with alkenes and has wide applications in the expanding fluorous research area

Pittogrammi

Health hazardExclamation mark

Avvertenze

Warning

Indicazioni di pericolo

Classi di pericolo

Acute Tox. 4 Oral - STOT RE 2 Inhalation

Organi bersaglio

Liver

Codice della classe di stoccaggio

10 - Combustible liquids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter


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Mitsue Sano et al.
Journal of mass spectrometry : JMS, 49(2), 128-135 (2014-03-29)
A method for the detection of unlabeled and (15)N2 -labeled L-tryptophan (L-Trp), L-kynurenine (L-Kyn), serotonin (5-HT) and quinolinic acid (QA) in human and rat plasma by GC/MS is described. Labeled and unlabeled versions of these four products were analyzed as
M Usami et al.
Kokuritsu Iyakuhin Shokuhin Eisei Kenkyujo hokoku = Bulletin of National Institute of Health Sciences, (118)(118), 45-49 (2001-09-06)
Teratogenicity of 2,2,3,3,3-pentafluoro-1-propanol (5FP), an alternative cleaning agent for chlorofluorocarbon, was examined in rats. 5FP was diluted with sesame oil and given to pregnant rats (Crj: Wistar) by gavage once a day from day 7 to 17 of pregnancy at
Patrick S Cardona et al.
Forensic science international, 157(1), 46-56 (2006-01-24)
A method was developed for simultaneously analyzing cocaine (COC), benzoylecgonine (BZE), norbenzoylecgonine (BNE), norcocaine (NCOC), ecgonine (ECG), ecgonine methyl ester (EME), m-hydroxybenzoylecgonine (HBZE), anhydroecgonine methyl ester (AEME), cocaethylene (CE), norcocaethylene (NCE), and ecgonine ethyl ester (EEE) in blood, urine, and
Sudha Manandhar et al.
The Journal of organic chemistry, 67(18), 6415-6420 (2002-08-31)
Interactions of various fluorinated and nonfluorinated alcohols with trans-stilbene in the presence of electrophilic reagents were studied. Under neat conditions, reactions of trans-stilbene (1) with fluorinated alcohols, R(f)OH (R(f) = CF3CH2-, CFH2CH2-, CF3CF2CH2-, CF2H(CF2)3CH2-, (CF3)2CH-, (CF3)3C- (2a-f) in the presence
Ishihara, T.; et al.
Tetrahedron, 62, 3783-3783 (2006)

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