226289

N,N-Dimethyltrimethylsilylamine

97%

• Sinonimo/i: (Dimethylamino)trimethylsilane, N-(Trimethylsilyl)dimethylamine, TMSDMA
• Formula condensata: (CH₃)₃SiN(CH₃)₂
• Numero CAS: 2083-91-2
• Peso molecolare: 117.26
• Beilstein: 1731861
• Numero CE: 218-222-3
• Numero MDL: MFCD00008297
• Codice UNSPSC: 12352100
• ID PubChem: 24853554
• NACRES: NA.22

Proprietà

• Livello qualitativo: 200
• Saggio: 97%
• Forma fisica: liquid
• Indice di rifrazione: n20/D 1.397 (lit.)
• P. eboll.: 84 °C (lit.)
• Densità: 0.732 g/mL at 25 °C (lit.)
• Gruppo funzionale: amine
• Stringa SMILE: CN(C)[Si](C)(C)C
• InChI: 1S/C5H15NSi/c1-6(2)7(3,4)5/h1-5H3; KAHVZNKZQFSBFW-UHFFFAOYSA-N

Descrizione

Applicazioni

N,N-Dimethyltrimethylsilylamine can be used as a reactant to prepare:

• Trifluoromethylacetophenone-N,N-dimethyltrimethylsilylamine adduct, which is used as an efficient reagent for nucleophilic trifluoromethylation of carbonyl and the imine group.
• (Dimethylamino)sulfur trifluoride (Me-DAST), which is employed as a deoxofluorinating agent for the conversion of aliphatic alcohols into their corresponding fluorides.
• Nucleoside phosphoramidites by reacting with alkyloxy (or aryloxy)-triazolylphosphine and deoxynucleoside.

It can also be used as a silylating agent in chemical synthesis.

Informazioni sulla sicurezza

• Pittogrammi: GHS02,GHS05
• Avvertenze: Danger
• Indicazioni di pericolo: H225,H260,H314
• Consigli di prudenza: P210 - P223 - P231 + P232 - P280 - P303 + P361 + P353 - P305 + P351 + P338
• Classi di pericolo: Eye Dam. 1 - Flam. Liq. 2 - Skin Corr. 1B - Water-react 1
• Codice della classe di stoccaggio: 4.3 - Hazardous materials which set free flammable gases upon contact with water
• Classe di pericolosità dell'acqua (WGK): WGK 3
• Punto d’infiammabilità (°F): 10.4 °F - closed cup
• Punto d’infiammabilità (°C): -12 °C - closed cup
• Dispositivi di protezione individuale: Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter