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Merck
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Key Documents

V900558

Sigma-Aldrich

Isopropyl myristate

Vetec, reagent grade, 98%

Sinônimo(s):

Isopropyl tetradecanoate, Myristic acid isopropyl ester

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About This Item

Fórmula linear:
CH3(CH2)12COOCH(CH3)2
Número CAS:
Peso molecular:
270.45
Beilstein:
1781127
Número CE:
Número MDL:
Código UNSPSC:
12352100
ID de substância PubChem:

grau

reagent grade

linha de produto

Vetec

Ensaio

98%

índice de refração

n20/D 1.434 (lit.)

pb

193 °C/20 mmHg (lit.)

pf

~3 °C (lit.)

densidade

0.85 g/mL at 25 °C (lit.)

cadeia de caracteres SMILES

CCCCCCCCCCCCCC(=O)OC(C)C

InChI

1S/C17H34O2/c1-4-5-6-7-8-9-10-11-12-13-14-15-17(18)19-16(2)3/h16H,4-15H2,1-3H3

chave InChI

AXISYYRBXTVTFY-UHFFFAOYSA-N

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Informações legais

Vetec is a trademark of Merck KGaA, Darmstadt, Germany

Código de classe de armazenamento

10 - Combustible liquids

Classe de risco de água (WGK)

awg

Ponto de fulgor (°F)

235.4 °F - closed cup

Ponto de fulgor (°C)

113 °C - closed cup


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Shishu Goindi et al.
International journal of pharmaceutics, 495(2), 913-923 (2015-10-13)
In this paper, we report an ionic liquid-in-water (IL/w) microemulsion (ME) formulation which is able to solubilize etodolac (ETO), a poorly water soluble drug for topical delivery using BMIMPF6 (1-butyl-3-methylimidazolium hexafluorophosphate) as IL, Tween 80 as surfactant and ethanol as
Ji Zhang et al.
International journal of pharmaceutics, 421(1), 34-44 (2011-10-01)
In this study, microemulsion microstructures, key formulation variables, and their relationship to drug transdermal permeation enhancement were investigated. A microemulsion system with high water soluble capacity was developed, using isopropyl myristate, Labrasol, and Cremophor EL as oil, surfactant, and co-surfactant
Qingping Tian et al.
International journal of pharmaceutics, 426(1-2), 202-210 (2012-01-26)
To improve the skin permeation of naproxen with larger dosage, microemulsion with high content of naproxen was investigated for transdermal delivery and its solubilization mechanism was studied. Naproxen micoremulsions composed of 4% isopropyl myristate, 18% Tween 80, 18% ethanol and
T N Engelbrecht et al.
Skin pharmacology and physiology, 25(4), 200-207 (2012-05-23)
In order to elucidate the mode of action of the lipophilic penetration enhancer isopropyl myristate (IPM) on a molecular scale, we investigated oriented quaternary stratum corneum (SC) lipid model membranes based on ceramide AP, cholesterol, palmitic acid and cholesterol sulfate
Qian Zhang et al.
Pharmaceutical research, 30(1), 32-40 (2012-08-28)
In principle, maximum transepidermal fluxes of solutes should be similar for different vehicles, except when the solute or vehicle modifies the skin. Here we estimated maximum flux, stratum corneum solubility, diffusivity and permeability coefficient for a range of similarly sized

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