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Documentos Principais

1705006

USP

L-Tyrosine

United States Pharmacopeia (USP) Reference Standard

Sinônimo(s):

(S)-2-Amino-3-(4-hydroxyphenyl)propionic acid, 3-(4-Hydroxyphenyl)-L-alanine

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About This Item

Fórmula linear:
4-(HO)C6H4CH2CH(NH2)CO2H
Número CAS:
Peso molecular:
181.19
Beilstein:
392441
Número MDL:
Código UNSPSC:
41116107
ID de substância PubChem:
NACRES:
NA.24

grau

pharmaceutical primary standard

família API

tyrosine

fabricante/nome comercial

USP

pf

>300 °C (dec.) (lit.)

aplicação(ões)

pharmaceutical (small molecule)

Formato

neat

cadeia de caracteres SMILES

N[C@@H](Cc1ccc(O)cc1)C(O)=O

InChI

1S/C9H11NO3/c10-8(9(12)13)5-6-1-3-7(11)4-2-6/h1-4,8,11H,5,10H2,(H,12,13)/t8-/m0/s1

chave InChI

OUYCCCASQSFEME-QMMMGPOBSA-N

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Descrição geral

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Aplicação

ʟ-Tyrosine USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:
  • Tyrosine
  • Glycyl-l-tyrosine
  • Levodopa
  • N-Acetyltyrosine
  • Hyaluronidase Injection

Outras notas

Amino acid precursor of dopamine and other catecholamines
This product is part of USP Biologics Program.
Sales restrictions may apply.

Nota de análise

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Código de classe de armazenamento

13 - Non Combustible Solids

Classe de risco de água (WGK)

WGK 1


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Andrzej Slominski et al.
Pigment cell & melanoma research, 25(1), 14-27 (2011-08-13)
There is evidence that L-tyrosine and L-dihydroxyphenylalanine (L-DOPA), besides serving as substrates and intermediates of melanogenesis, are also bioregulatory agents acting not only as inducers and positive regulators of melanogenesis but also as regulators of other cellular functions. These can
Maria B Feeney et al.
Antioxidants & redox signaling, 17(11), 1571-1579 (2012-03-20)
The understanding of physiological and pathological processes involving protein oxidation, particularly under conditions of aging and oxidative stress, can be aided by proteomic identification of proteins that accumulate oxidative post-translational modifications only if these detected modifications are connected to functional
Verena Rahm et al.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 55(4), 546-550 (2014-02-26)
Low-grade gliomas (LGGs) may harbor malignant foci, which are characterized by increased tumor cellularity and angiogenesis. We used diffusion-weighted MR imaging (apparent diffusion coefficient [ADC]) and PET with the amino acid O-(2-(18)F-fluorethyl)-L-tyrosine ((18)F-FET) to search for focal changes of diffusion
Daniel T Patton et al.
Journal of immunology (Baltimore, Md. : 1950), 193(7), 3446-3455 (2014-08-22)
IL-7 is critical for murine T and B cell development and survival and plays a significant role in lymphoblastic leukemia in both humans and mice. We evaluated the role of the IL-7Rα Tyr(449) cytoplasmic SH2-binding motif in IL-7-mediated B cell
Sharon L Bourke et al.
Advanced drug delivery reviews, 55(4), 447-466 (2003-04-23)
The natural amino acid L-tyrosine is a major nutrient having a phenolic hydroxyl group. This feature makes it possible to use derivatives of tyrosine dipeptide as a motif to generate diphenolic monomers, which are important building blocks for the design

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