1458009
USP
Neomycin sulfate
United States Pharmacopeia (USP) Reference Standard
Sinônimo(s):
Neomycin trisulfate salt, Neomycin B sulfate
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About This Item
Fórmula empírica (Notação de Hill):
C23H46N6O13 · 3H2SO4
Número CAS:
Peso molecular:
908.88
Código UNSPSC:
41116107
NACRES:
NA.24
Produtos recomendados
grau
pharmaceutical primary standard
família API
neomycin
fabricante/nome comercial
USP
aplicação(ões)
pharmaceutical (small molecule)
formato
neat
InChI
1S/C23H46N6O13.H2O4S/c24-2-7-13(32)15(34)10(28)21(37-7)40-18-6(27)1-5(26)12(31)20(18)42-23-17(36)19(9(4-30)39-23)41-22-11(29)16(35)14(33)8(3-25)38-22;1-5(2,3)4/h5-23,30-36H,1-4,24-29H2;(H2,1,2,3,4)/t5-,6+,7-,8+,9-,10-,11-,12+,13-,14-,15-,16-,17-,18-,19-,20-,21-,22?,23+;/m1./s1
chave InChI
OIXVKQDWLFHVGR-GQTDVWSESA-N
Descrição geral
Neomycin Sulfate is the sulfate salt of a kind of neomycin, an antibacterial substance produced by the growth of Streptomyces fradiae Waksman (Fam. Streptomycetaceae), or a mixture of two or more such salts, the main component being neomycin B sulfate. It has a potency equivalent to NLT 600 µg of neomycin/mg, calculated on the dried basis.
Neomycin sulfate USP reference standard is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including MSDS and any product information leaflets, has been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.
Neomycin sulfate USP reference standard is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including MSDS and any product information leaflets, has been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.
Aplicação
Neomycin sulfate USP reference standard intended for use in specified quality tests and assays. It is also used to prepare sample solution for assay of Polymyxin B according to the given below monographs of United States Pharmacopeia (USP):
- Neomycin and Polymyxin B Sulfates and Hydrocortisone Ophthalmic Suspension
- Neomycin and Polymyxin B Sulfates Ophthalmic Ointment
- Neomycin and Polymyxin B Sulfates, Bacitracin Zinc, and Lidocaine Ointment
- Neomycin and Polymyxin B Sulfates and Lidocaine Cream
- Neomycin Sulfate and Hydrocortisone Otic Suspension
- Neomycin and Polymyxin B Sulfates and Hydrocortisone Otic Suspension
Further information is available in the monograph, Neomycin Sulfate, USP43-NF38 - 3120, USP43-NF38 - 3126, etc of the USP (United States Pharmacopeia).
Atenção
Stock solutions should be filter sterilized and stored at 2-8°C, and are stable at 37°C for 5 days. A 1 mg/mL neomycin solution in .1 M phosphate buffer, pH 8.0 should be used within 14 days when stored at 0-5°C. Solutions should be protected from light or moisture.
Nota de preparo
Neomycin sulfate is soluble in H2O at 50 mg/mL, yielding a clear solution.
Outras notas
This product is part of the USP Biologics program.
Informações legais
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.
Palavra indicadora
Danger
Frases de perigo
Declarações de precaução
Classificações de perigo
Resp. Sens. 1 - Skin Sens. 1
Código de classe de armazenamento
11 - Combustible Solids
Classe de risco de água (WGK)
WGK 3
Ponto de fulgor (°F)
Not applicable
Ponto de fulgor (°C)
Not applicable
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