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1279804

USP

Fluoxetine hydrochloride

United States Pharmacopeia (USP) Reference Standard

Sinônimo(s):

(±)-N-Methyl-γ-[4-(trifluoromethyl)phenoxy]benzenepropanamine hydrochloride, LY-110,140 hydrochloride, Prozac®

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About This Item

Fórmula empírica (Notação de Hill):
C17H18F3NO · HCl
Número CAS:
56296-78-7
Peso molecular:
345.79
Número MDL:
MFCD00214288
Código UNSPSC:
41116107
ID de substância PubChem:
329749876
NACRES:
NA.24

grau

pharmaceutical primary standard

família API

fluoxetine

fabricante/nome comercial

USP

aplicação(ões)

pharmaceutical (small molecule)

formato

neat

cadeia de caracteres SMILES

CNCCC(C1=CC=CC=C1)OC2=CC=C(C(F)(F)F)C=C2.[H]Cl

InChI

1S/C17H18F3NO.ClH/c1-21-12-11-16(13-5-3-2-4-6-13)22-15-9-7-14(8-10-15)17(18,19)20;/h2-10,16,21H,11-12H2,1H3;1H

chave InChI

GIYXAJPCNFJEHY-UHFFFAOYSA-N

Informações sobre genes

human ... SLC6A4(6532)

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Aplicação

Fluoxetine hydrochloride USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:
  • Fluoxetine Tablets
  • Fluoxetine Delayed-Release Capsules
  • Olanzapine and Fluoxetine Capsules
  • Fluoxetine Oral Solution
  • Fluoxetine Capsules

Ações bioquímicas/fisiológicas

Selective serotonin reuptake inhibitor; antidepressant.

Nota de análise

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Outras notas

Sales restrictions may apply.

Informações legais

Sold under license from Eli Lilly and Company.
Prozac is a registered trademark of Eli Lilly and Co.

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Fluoxetine impurity C, European Pharmacopoeia (EP) Reference Standard

1279826

Fluoxetine Related Compound B, United States Pharmacopeia (USP) Reference Standard

1279837

Fluoxetine Related Compound C, United States Pharmacopeia (USP) Reference Standard

1279815

Fluoxetine Related Compound A, United States Pharmacopeia (USP) Reference Standard

BP797

Fluoxetine hydrochloride, British Pharmacopoeia (BP) Reference Standard

PHR1953

Fluoxetine Related Compound C, Pharmaceutical Secondary Standard; Certified Reference Material

PHR1952

Fluoxetine Related Compound A, Pharmaceutical Secondary Standard; Certified Reference Material

PHR2041

Fluoxetine Related Compound B, Pharmaceutical Secondary Standard; Certified Reference Material

Y0002201

Fluoxetine impurity A, CRS, European Pharmacopoeia (EP) Reference Standard

Y0002219

Fluoxetine hydrochloride for ID and assay, CRS, European Pharmacopoeia (EP) Reference Standard

Palavra indicadora

Danger

Frases de perigo

H302,H318,H336,H373,H410

Classificações de perigo

Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Dam. 1 - STOT RE 2 - STOT SE 3

Órgãos-alvo

Central nervous system

Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

Certificados de análise (COA)

Busque Certificados de análise (COA) digitando o Número do Lote do produto. Os números de lote e remessa podem ser encontrados no rótulo de um produto após a palavra “Lot” ou “Batch”.

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R J Gonzalez-Rothi et al.
Chest, 107(6), 1763-1765 (1995-06-01)
We describe a patient who developed progressive dyspnea, lung infiltrates, and restrictive lung disease in association with the antidepressant fluoxetine hydrochloride (Prozac). The pathologic findings were consistent with hypersensitivity pneumonitis. An associated pulmonary phospholipidosis was also noted.
Paulina Jedynak et al.
Journal of psychiatric research, 56, 106-111 (2014-06-17)
The neurogenesis hypothesis of major depression has two main facets. One states that the illness results from decreased neurogenesis while the other claims that the very functioning of antidepressants depends on increased neurogenesis. In order to verify the latter, we
Kristie T Ota et al.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 40(3), 711-718 (2014-09-03)
Major depressive disorder (MDD) is a debilitating and widespread illness that exerts significant personal and socioeconomic consequences. Recent genetic and brain-imaging studies suggest that bicaudal C homolog 1 gene (BICC1), which codes for an RNA-binding protein, may be associated with
Sean C Godar et al.
Journal of psychiatric research, 56, 1-9 (2014-06-03)
The termination of serotonin (5-hydroxytryptamine, 5-HT) neurotransmission is regulated by its uptake by the 5-HT transporter (5-HTT), as well as its degradation by monoamine oxidase (MAO)-A. MAO-A deficiency results in a wide set of behavioral alterations, including perseverative behaviors and
Rody Kingston et al.
PLoS genetics, 17(11), e1009885-e1009885 (2021-11-05)
Molecular insights into the selective vulnerability of retinal ganglion cells (RGCs) in optic neuropathies and after ocular trauma can lead to the development of novel therapeutic strategies aimed at preserving RGCs. However, little is known about what molecular contexts determine
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