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1278007

USP

Fluorometolona

United States Pharmacopeia (USP) Reference Standard

Sinônimo(s):

11β,17α-Di-hidroxi-9-fluoro-6-metil-1,4-pregnadieno-3,20-diona

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About This Item

Fórmula empírica (Notação de Hill):
C22H29FO4
Número CAS:
426-13-1
Peso molecular:
376.46
Número MDL:
MFCD00056461
Código UNSPSC:
41116107
ID de substância PubChem:
329749869
NACRES:
NA.24

grau

pharmaceutical primary standard

família API

fluorometholone

fabricante/nome comercial

USP

aplicação(ões)

pharmaceutical (small molecule)

formato

neat

cadeia de caracteres SMILES

C[C@H]1C[C@H]2[C@@H]3CC[C@](O)(C(C)=O)[C@@]3(C)C[C@H](O)[C@]2(F)[C@@]4(C)C=CC(=O)C=C14

InChI

1S/C22H29FO4/c1-12-9-17-15-6-8-21(27,13(2)24)20(15,4)11-18(26)22(17,23)19(3)7-5-14(25)10-16(12)19/h5,7,10,12,15,17-18,26-27H,6,8-9,11H2,1-4H3/t12-,15-,17-,18-,19-,20-,21-,22-/m0/s1

chave InChI

FAOZLTXFLGPHNG-KNAQIMQKSA-N

Informações sobre genes

human ... NR3C1(2908)

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Descrição geral

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Aplicação

Fluorometholone USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:
  • Fluorometholone Acetate
  • Fluorometholone Ophthalmic Suspension
  • Hydrocortisone Hemisuccinate
  • Hydrocortisone Sodium Succinate for Injection
  • Methylprednisolone Hemisuccinate
  • Methylprednisolone Sodium Succinate for Injection

Ações bioquímicas/fisiológicas

Clinicamente significativo em conjuntivite alérgica e como anti-inflamatório após cirurgia de catarata.

Nota de análise

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Outras notas

Sales restrictions may apply.

Pictogramas

Exclamation mark
GHS07

Palavra indicadora

Warning

Frases de perigo

H302 + H312 + H332

Classificações de perigo

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral

Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

Certificados de análise (COA)

Busque Certificados de análise (COA) digitando o Número do Lote do produto. Os números de lote e remessa podem ser encontrados no rótulo de um produto após a palavra “Lot” ou “Batch”.

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Asimina Mataftsi et al.
The British journal of ophthalmology, 95(11), 1531-1533 (2011-02-08)
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Wenjia Xie et al.
Investigative ophthalmology & visual science, 55(9), 5806-5812 (2014-08-26)
To investigate the effect on tear menisci after laser in situ keratomileusis (LASIK) with flap creation by either microkeratome or femtosecond laser. Sixty eyes of 30 myopes were analyzed. Fifteen patients underwent LASIK with Moria II microkeratome, and the other
Hua Gao et al.
Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 252(6), 963-968 (2014-05-07)
To evaluate the feasibility of partial lamellar keratoplasty (LK) for treatment of peripheral corneal disease (PCD) using a graft from the corneoscleral rim preserved in glycerin. Patients who underwent LK for PCD at Shandong Eye Hospital from January 2006 to
Miaomiao Zhang et al.
Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 252(6), 983-987 (2014-03-29)
To analyze the efficacy of selective laser trabeculoplasty (SLT) on silicone oil-induced secondary glaucoma in terms of intraocular pressure (IOP). 42 patients (42 eyes) with silicone oil-induced secondary glaucoma were selected, and SLT was performed with 360° of the trabecular
Lingmin He et al.
JAMA ophthalmology, 133(1), 51-59 (2014-10-17)
Wavefront-guided (WFG) and wavefront-optimized (WFO) platforms for refractive surgery are designed for improved visual outcomes. It is unclear which treatment profile is superior for patients undergoing photorefractive keratectomy (PRK). To compare the safety, efficacy, predictability, stability, and higher-order aberrations in
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