1134357

Cisplatin

United States Pharmacopeia (USP) Reference Standard

• Sinônimo(s): cis-Diammineplatinum(II) dichloride, cis-Dichlorodiammine platinum(II), cis-Platinum(II) diammine dichloride, Cisplatin
• Fórmula linear: Pt(NH₃)₂Cl₂
• Número CAS: 15663-27-1
• Peso molecular: 300.05
• Número MDL: MFCD00011623
• Código UNSPSC: 41116107
• ID de substância PubChem: 329749409
• NACRES: NA.24

Propriedades

• grau: pharmaceutical primary standard
• família API: cisplatin
• fabricante/nome comercial: USP
• pf: 270 °C (lit.)
• aplicação(ões): pharmaceutical (small molecule)
• formato: neat
• cadeia de caracteres SMILES: N.N.Cl[Pt]Cl
• InChI: 1S/2ClH.2H3N.Pt/h2*1H;2*1H3;/q;;;;+2/p-2
• chave InChI: LXZZYRPGZAFOLE-UHFFFAOYSA-L

Descrição

Descrição geral

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Aplicação

Cisplatin USP reference standard for use in specified quality tests and assays.

Also used to prepare standard and system suitability solution for assay and impurity analysis according to the given below monographs of United States Pharmacopeia (USP):

• Cisplatin
• Cisplatin for Injection
• Carboplatin Injection

Ações bioquímicas/fisiológicas

Potent platinum-based antineoplastic agent. Forms cytotoxic adducts with the DNA dinucleotide d(pGpG), inducing intrastrand cross-links.

Nota de análise

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Outras notas

Sales restrictions may apply.

Informações de segurança

• Pictogramas: GHS06,GHS08
• Palavra indicadora: Danger
• Frases de perigo: H300 - H315 - H317 - H319 - H334 - H335 - H350
• Declarações de precaução: P201 - P280 - P301 + P310 - P302 + P352 - P304 + P340 + P312 - P305 + P351 + P338
• Classificações de perigo: Acute Tox. 2 Oral - Carc. 1B - Eye Irrit. 2 - Resp. Sens. 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3
• Órgãos-alvo: Respiratory system
• Código de classe de armazenamento: 6.1A - Combustible, acute toxic Cat. 1 and 2 / very toxic hazardous materials
• Classe de risco de água (WGK): WGK 3
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable