581424-U
Ascentis® C8 (5 µm) HPLC Columns
L × I.D. 15 cm × 4.6 mm, HPLC Column
Sinônimo(s):
C8 Reversed-Phase Column
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About This Item
Código UNSPSC:
41115700
eCl@ss:
32110501
NACRES:
SB.52
Produtos recomendados
Nome do produto
Ascentis® C8 HPLC Column, 5 μm particle size, L × I.D. 15 cm × 4.6 mm
Materiais
stainless steel column
Agency
suitable for USP L7
linha de produto
Ascentis®
Características
endcapped
fabricante/nome comercial
Ascentis®
embalagem
1 ea of
Extensão da rotulagem
15% Carbon loading
Parâmetros
≤70 °C temp. range
400 bar pressure (5801 psi)
técnica(s)
HPLC: suitable
LC/MS: suitable
C × D.I.
15 cm × 4.6 mm
área da superfície
450 m2/g
cobertura de superfície
4.0 μmol/m2
Impurezas
<5 ppm metals
Matriz
fully porous particle
silica gel high purity, spherical
Grupo ativo da matriz
C8 (octyl) phase
tamanho de partícula
5 μm
tamanho de poro
100 Å
Faixa de pH operacional
2-8
aplicação(ões)
food and beverages
técnica de separação
reversed phase
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Descrição geral
The Ascentis family of columns is the fourth generation of HPLC column technology from Supelco scientists. Ascentis columns are bonded on high purity, 100 Angstrom silica including 3, 5, and 10 micron particle size. Columns are designed for small molecule applications and are scalable from micro columns (1.0 mm I.D.) to preparative dimensions (50 mm I.D.). The family includes C18, C8, Phenyl, Si and embedded polar group phase, RP-Amide.
The Ascentis C8 is a highly reproducible column with excellent selectivity towards polar compounds. The phase excells in highly aqueous mobile phases as well as high organic mobile phases.
The Ascentis C8 is a highly reproducible column with excellent selectivity towards polar compounds. The phase excells in highly aqueous mobile phases as well as high organic mobile phases.
Aplicação
- Analysis of 27 beta-Blockers and Metabolites in Milk Powder by High Performance Liquid Chromatography Coupled to Quadrupole Orbitrap High-Resolution Mass Spectrometry.: This study utilizes the Ascentis® C8 HPLC Column to analyze beta-blockers and their metabolites in milk powder, highlighting the column′s capacity for sensitive and precise quantification in complex matrices (Cheng et al., 2019).
- Recent trends in ultra-fast HPLC: new generation superficially porous silica columns.: A review of advancements in HPLC technology, including the use of Ascentis® C8 columns, which enhance the speed and efficiency of chemical separations (Ali et al., 2012).
- Superficially porous particles columns for super fast HPLC separations.: Discusses the benefits of using Ascentis® C8 HPLC Columns for achieving faster and more efficient separations in HPLC, underlining their utility in high-throughput settings (Ali et al., 2012).
- Gradient RP-HPLC method for the determination of potential impurities in atazanavir sulfate.: Demonstrates the effectiveness of the Ascentis® C8 HPLC Column in a robust method for identifying impurities in pharmaceutical compounds, ensuring product safety and compliance (Chitturi et al., 2011).
- Development and validation of an HPLC-MS/MS method to determine clopidogrel in human plasma. Use of incurred samples to test back-conversion.: Illustrates the application of Ascentis® C8 HPLC Column in a validated method for the analysis of clopidogrel, improving therapeutic drug monitoring and patient care (Silvestro et al., 2010).
Características e benefícios
- Superior retention for hydrophobic molecules
- Excellent peak shape
- Low bleed LC-MS separations
Informações legais
Ascentis is a registered trademark of Merck KGaA, Darmstadt, Germany
produto relacionado
Código de classe de armazenamento
13 - Non Combustible Solids
Classe de risco de água (WGK)
WGK 1
Ponto de fulgor (°F)
Not applicable
Ponto de fulgor (°C)
Not applicable
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Gastrointestinal stability of venlafaxine was evaluated in vitro in simulated gastric (SGF) and intestinal (SIF) fluids using a stability indicating HPLC method. The method was validated using a 5 microm Ascentis C18 column (150 mm x 4.6 mm) and mobile
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This paper proposes a simple and selective RP-HPLC method for the determination of process impurities and degradation products (degradants) of atazanavir sulfate (ATV) drug substance. Chromatographic separation was achieved on Ascentis(®) Express C8, (150mm×4.6mm, 2.7μm) column thermostated at 30°C under
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