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Key Documents

53848-U

Supelco

Ascentis® Express 90Å C8 (2.7 μm) HPLC Columns

L × I.D. 5 cm × 3 mm, HPLC Column

Sinônimo(s):

Core-shell (SPP) Fused Core C8 HPLC column

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About This Item

Código UNSPSC:
41115700
eCl@ss:
32110501
NACRES:
SB.52

product name

Ascentis® Express C8, 2.7 μm HPLC Column, 2.7 μm particle size, L × I.D. 5 cm × 3 mm

Materiais

stainless steel column

Agency

suitable for USP L7

linha de produto

Ascentis®

Características

endcapped

fabricante/nome comercial

Ascentis®

embalagem

1 ea of

Parâmetros

60 °C temp. range
600 bar max. pressure (9000 psi)

técnica(s)

HPLC: suitable
LC/MS: suitable
UHPLC-MS: suitable
UHPLC: suitable

C × D.I.

5 cm × 3 mm

área da superfície

135 m2/g

Impurezas

<5 ppm metals

matriz

Fused-Core particle platform
superficially porous particle

Grupo ativo da matriz

C8 (octyl) phase

tamanho de partícula

2.7 μm

tamanho de poro

90 Å

operating pH range

2-9

aplicação(ões)

food and beverages

técnica de separação

reversed phase

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Descrição geral

Ascentis Express HPLC columns, through the use of Fused-Core® particle technology, can provide you with both the high speed and high efficiencies of sub-2 μm particles while maintaining lower backpressures. The combination of high efficiency and low backpressure benefits UPLC® (or other ultra high pressure system) users, as well as conventional HPLC users.
Visit the Ascentis Express home page for more information on this new column technology.

Aplicação


  • Recent trends in ultra-fast HPLC: new generation superficially porous silica columns: This review explores advancements in high-performance liquid chromatography (HPLC), specifically focusing on the Ascentis® Express C8 column. Highlighting its role in achieving high-efficiency separations due to its design, this column is ideal for rapid, high-resolution chromatographic analysis in pharmaceutical, environmental, and material science applications (Ali et al., 2012).

  • Quality by design approach for the separation of naproxcinod and its related substances by fused core particle technology column: This research employs the Ascentis® Express C8 column, utilizing its high-efficiency and rapid separation capabilities to analyze naproxcinod and its impurities. The study exemplifies the column′s use in pharmaceutical quality control, ensuring drug purity and safety (Inugala et al., 2013).

Informações legais

Ascentis is a registered trademark of Merck KGaA, Darmstadt, Germany
Fused-Core is a registered trademark of Advanced Materials Technology, Inc.
UPLC is a registered trademark of Waters

Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable


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Visite a Biblioteca de Documentos

Ugandar Reddy Inugala et al.
Journal of chromatographic science, 51(5), 453-459 (2012-10-13)
This paper describes the development of a rapid, novel, stability-indicating gradient reversed-phase high-performance liquid chromatographic method and associated system suitability parameters for the analysis of naproxcinod in the presence of its related substances and degradents using a quality-by-design approach. All
Sreenivasa Rao Chitturi et al.
Journal of pharmaceutical and biomedical analysis, 55(1), 31-47 (2011-02-15)
This paper proposes a simple and selective RP-HPLC method for the determination of process impurities and degradation products (degradants) of atazanavir sulfate (ATV) drug substance. Chromatographic separation was achieved on Ascentis(®) Express C8, (150mm×4.6mm, 2.7μm) column thermostated at 30°C under
Federica Pellati et al.
Journal of pharmaceutical and biomedical analysis, 81-82, 126-132 (2013-05-07)
A closed-vessel microwave-assisted extraction (MAE) technique was optimized for the first time for the extraction of polyphenols from raw propolis. The results obtained by means of response surface experimental design methodology showed that the best global response was reached when
Monika A Olszewska
Journal of separation science, 35(17), 2174-2183 (2012-07-19)
An HPLC method of high resolution has been developed and validated for the simultaneous determination of ten prominent flavonoid aglycones in plant materials using a fused-core C18-silica column (Ascentis® Express, 4.6 mm × 150 mm, 2.7 μm). The separation was
Imran Ali et al.
Biomedical chromatography : BMC, 26(8), 1001-1008 (2012-01-13)
Superficially porous silica particles columns (SPSPCs) are manufactured by different companies. The most common have the brand names Halo, Ascentis Express and Kinetex. These columns provide super fast, sharp peaks and moderate sample loading and back pressure. These are available

Artigos

Sigma-Aldrich presents an article on serum lipidomics profiling using an Ascentis Express Fused-Core C18 column.

When a C18 doesn′t give the desired separation, or your sample contains compounds that are known to be difficult to retain or resolve on a C18, consider changing to an Ascentis® Express C8 column.

Chromatograms

application for HPLC

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