V9014

Anti-VMAT2 antibody produced in rabbit

~1 mg/mL, affinity isolated antibody, buffered aqueous solution

• Sinônimo(s): Anti-SLC18A2, Anti-SVAT, Anti-SVMT, Anti-Solute carrier family 18 (vesicular monoamine), member 2, Anti-VAT2, Anti-VMAT2
• Número MDL: MFCD02097601
• Código UNSPSC: 12352203
• NACRES: NA.41

Propriedades

• fonte biológica: rabbit
• Nível de qualidade: 200
• conjugado: unconjugated
• forma do anticorpo: affinity isolated antibody
• tipo de produto de anticorpo: primary antibodies
• clone: polyclonal
• Formulário: buffered aqueous solution
• reatividade de espécies: mouse, rat, human
• concentração: ~1 mg/mL
• técnica(s): immunohistochemistry: 1:100-1:250; western blot: 1:500-1:1,000
• nº de adesão UniProt: Q05940
• Condições de expedição: dry ice
• temperatura de armazenamento: −20°C
• modificação pós-traducional do alvo: unmodified
• Informações sobre genes: human ... SLC18A2(6571) ; mouse ... Slc18a2(214084) ; rat ... Slc18a2(25549)

Descrição

Descrição geral

Vesicular monoamine transporter 2 (VMAT2) , also known as solute carrier family 18 member A2 (SLC18A2), is a transmembrane protein that acts at nerve terminals. It is expressed in platelets and in central, peripheral and enteric neurons. The gene encoding VMAT2 consists of 16 exons and is mapped to human chromosome 10q25.

Imunogênio

synthetic peptide corresponding an internal sequence of human VMAT2. This sequence is identical in mouse and rat.

Aplicação

Anti-VMAT2 antibody produced in rabbit has also been used in immunofluorescence.

Anti-VMAT2 antibody produced in rabbit has been used in western blot analysis.

Ações bioquímicas/fisiológicas

Vesicular monoamine transporter 2 (VMAT2) modulates the release of neurotransmitters like dopamine, serotonin and γ-amino butyric acid. It has a role in the accumulation of neurotransmitters in synaptic vesicles to prevent toxicity. VMAT2 has been linked to tardive dyskinesia and may be associated with Parkinson′s disease.

forma física

solution in phosphate buffered saline, containing 0.02% sodium azide.

Exoneração de responsabilidade

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informações de segurança

• Código de classe de armazenamento: 10 - Combustible liquids
• Classe de risco de água (WGK): nwg
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable
• Equipamento de proteção individual: Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)