T2379

Tubocurarine hydrochloride pentahydrate

≥97%

• Sinônimo(s): (+)-Tubocurarine hydrochloride
• Fórmula empírica (Notação de Hill): C₃₇H₄₁ClN₂O₆ · HCl · 5H₂O
• Número CAS: 6989-98-6
• Peso molecular: 771.72
• Número MDL: MFCD00150157
• Código UNSPSC: 12352200
• ID de substância PubChem: 24900034
• NACRES: NA.77

Propriedades

• Nível de qualidade: 200
• Ensaio: ≥97%
• solubilidade: H₂O: soluble 50 mg/ml, with heating as required, clear to slightly hazy, colorless to yellow; ethanol: soluble; methanol: soluble
• temperatura de armazenamento: 2-8°C
• cadeia de caracteres SMILES: O.O.O.O.O.Cl.[Cl-].COc1cc2CCN(C)[C@H]3Cc4ccc(Oc5c(O)c(OC)cc6CC[N+](C)(C)[C@H](Cc7ccc(O)c(Oc1cc23)c7)c56)cc4
• InChI: 1S/C37H40N2O6.2ClH.5H2O/c1-38-14-12-24-19-32(42-4)33-21-27(24)28(38)16-22-6-9-26(10-7-22)44-37-35-25(20-34(43-5)36(37)41)13-15-39(2,3)29(35)17-23-8-11-30(40)31(18-23)45-33;;;;;;;/h6-11,18-21,28-29H,12-17H2,1-5H3,(H-,40,41);2*1H;5*1H2/t28-,29+;;;;;;;/m0......./s1
• chave InChI: WMIZITXEJNQAQK-GGDSLZADSA-N
• Informações sobre genes: human ... CHRNA1(1134) , CHRNB1(1140) , CHRND(1144) , CHRNE(1145) , CHRNG(1146)

Descrição

Aplicação

Tubocurarine hydrochloride pentahydrate has been used as a acetylcholinesterase inhibitor (Ach) inhibitor in myotubes, muscle and as neuromuscular junction blocker in zebra fish embryos.

Ações bioquímicas/fisiológicas

Tubocurarine is a muscle relaxant and a nicotinic acetylcholine receptor antagonist. It can induce neuromuscular blocking.

Características e benefícios

This compound is featured on the Potassium Channels page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Nota de preparo

Tubocurarine hydrochloride pentahydrate is soluble in water at 50 mg/ml (with heat as required) and yields a clear to slightly hazy, colorless to yellow solution. It is also soluble in methanol and ethanol.

Informações de segurança

• Pictogramas: GHS06
• Palavra indicadora: Danger
• Frases de perigo: H301
• Declarações de precaução: P264 - P270 - P301 + P310 + P330 - P405 - P501
• Classificações de perigo: Acute Tox. 3 Oral
• Código de classe de armazenamento: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• Classe de risco de água (WGK): WGK 3
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable
• Equipamento de proteção individual: Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges