SRP5251

PKC-α, active, GST tagged from Xanopus sp.

PRECISIO^®, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution

• Sinônimo(s): MGC82897, PRKCA
• Código UNSPSC: 12352200
• NACRES: NA.32

Propriedades

• fonte biológica: Xenopus sp.
• recombinante: expressed in baculovirus infected Sf9 cells
• linha de produto: PRECISIO^®
• Ensaio: ≥70% (SDS-PAGE)
• forma: buffered aqueous glycerol solution
• atividade específica: 186-290 nmol/min·mg
• peso molecular: ~103 kDa
• nº de adesão NCBI: BC078065
• aplicação(ões): cell analysis
• Condições de expedição: dry ice
• temperatura de armazenamento: −70°C
• Informações sobre genes: Xenopus laevis ... prkca(447031)

Descrição

Descrição geral

Protein kinase C-α (PKC-α) is a member of the PKC family of serine- and threonine-specific protein kinases that can be activated by calcium and the secondary messenger diacylglycerol. The protein is expressed in the dorsal ectoderm of Xenopus.

Ações bioquímicas/fisiológicas

Protein kinase C-α (PKC-α) has been reported to play roles in many different cellular processes, such as cell adhesion, cell transformation, cell cycle checkpoint and cell volume control. It has been identified as a fundamental regulator of cardiac contractility and Ca²⁺ handling in myocytes.

forma física

Supplied in 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 10 mM glutathione, 0.1 mM EDTA, 0.25 mM DTT, 0.1 mM PMSF, 25% glycerol.

Nota de preparo

After opening, aliquot into smaller quantities and store at -70 °C. Avoid repeating handling and multiple freeze/thaw cycles.

Informações legais

PRECISIO is a registered trademark of Merck KGaA, Darmstadt, Germany

Informações de segurança

• Código de classe de armazenamento: 10 - Combustible liquids
• Classe de risco de água (WGK): WGK 1
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable