SRP4639

BMP-13 human

recombinant, expressed in E. coli, ≥95% (SDS-PAGE)

• Sinônimo(s): CDMP-2, Cartilage-Derived Morphogenetic Protein-2, GDF-6, bone morphogenetic protein 13
• Código UNSPSC: 12352202
• NACRES: NA.32

Propriedades

• fonte biológica: human
• recombinante: expressed in E. coli
• Ensaio: ≥95% (SDS-PAGE)
• forma: lyophilized
• potência: 0.5-4 μg/mL ED₅₀ (determined by its ability to induce alkaline phosphatase production by ATDC-5 chondrogenic cells.)
• peso molecular: ~27 kDa
• embalagem: pkg of 50 μg
• condição de armazenamento: avoid repeated freeze/thaw cycles
• Impurezas: endotoxin, tested
• nº de adesão NCBI: Q6KF10
• Condições de expedição: wet ice
• temperatura de armazenamento: −20°C
• Informações sobre genes: human ... GDF6(392255)

Descrição

Descrição geral

BMPs (bone morphogenetic proteins) belong to the TGF-β superfamily of structurally related signaling proteins. These ligands mediate numerous physiological processes. BMPs initiate, promote and maintain cartilage and bone development, growth, remodeling and repair, in both prenatal development and postnatal growth of eye, heart, kidney, skin, and other tissues. Expression of BMP-13 has been found in the hypertrophic chondrocytes of ossifying long bone centers. Recombinant human BMP-13/CDMP-2 is a 27 kDa homodimeric disulfide-linked protein consisting of two 120 amino acids polypeptide chains.

forma física

Sterile filtered and Lyophilized without additives.

Reconstituição

Centrifuge the vial prior to opening. Avoid freeze-thaw cycles.

Reconstitute to 0.1-1.0 mg/mL in water containing BSA (50 μg BSA per 1 μg of protein).