Pular para o conteúdo
Merck
Todas as fotos(1)

Documentos Principais

Visualizar Toda a Documentação

SML1606

Sigma-Aldrich

Oseltamivir phosphate

≥98% (HPLC)

Sinônimo(s):

GS4104, (3R,4R,5S)-4-Acetamido-5-amino-3-(1-ethylpropoxy)-1-cyclohexene-1-carboxylic acid ethyl ester phosphate salt

Faça loginpara ver os preços organizacionais e de contrato
Todas as fotos(1)

About This Item

Fórmula empírica (Notação de Hill):
C16H28N2O4 ·H3PO4
Número CAS:
204255-11-8
Peso molecular:
410.40
Número MDL:
MFCD08059548
Código UNSPSC:
12352200
ID de substância PubChem:
329825492
NACRES:
NA.77

Nível de qualidade

100

Ensaio

≥98% (HPLC)

Formulário

powder

atividade óptica

[α]/D -26 to -36°, c = 1 in H2O

cor

white to beige

solubilidade

H2O: 30 mg/mL, clear

temperatura de armazenamento

−20°C

cadeia de caracteres SMILES

OP(O)(O)=O.CCOC(=O)C1=C[C@@H](OC(CC)CC)[C@H](NC(C)=O)[C@@H](N)C1

InChI

1S/C16H28N2O4.H3O4P/c1-5-12(6-2)22-14-9-11(16(20)21-7-3)8-13(17)15(14)18-10(4)19;1-5(2,3)4/h9,12-15H,5-8,17H2,1-4H3,(H,18,19);(H3,1,2,3,4)/t13-,14+,15+;/m0./s1

chave InChI

PGZUMBJQJWIWGJ-ONAKXNSWSA-N

Procurando produtos similares? Visita Guia de comparação de produtos

Categorias relacionadas

Ações bioquímicas/fisiológicas

Oseltamivir phosphate is an influenza viral neuraminidase inhibitor. Oseltamivir phosphate, an antiviral, is used clinically to treat influenza A and influenza B, and to prevent flu after exposure. Oseltamivir phosphate is hydrolyzed in the liver to its active form, oseltamivir carboxylate, which is an inhibitor of influenza viral neuraminidases essential for viral replication. Oseltamivir has a broad spectrum of activity against a range of influenza A and B subtypes with IC50 values for neuraminidases measured from less than 1 nM to approximately 30 nM, depending on the virus subtype.

Pictogramas

Exclamation mark
GHS07

Palavra indicadora

Warning

Frases de perigo

H317,H319,H412

Classificações de perigo

Aquatic Chronic 3 - Eye Irrit. 2 - Skin Sens. 1

Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

Escolha uma das versões mais recentes:

Certificados de análise (COA)

Lot/Batch Number
017M4745V
066M4734V

Não está vendo a versão correta?

Se precisar de uma versão específica, você pode procurar um certificado específico pelo número do lote ou da remessa.

Pesquise por COA

Já possui este produto?

Encontre a documentação dos produtos que você adquiriu recentemente na biblioteca de documentos.

Visite a Biblioteca de Documentos

Os clientes também visualizaram

Slide 1 of 5

1 of 5

Mupirocin ≥92% (HPLC), powder

Sigma-Aldrich

M7694

Mupirocin

Tobramycin Aminoglycoside antibiotic

Sigma-Aldrich

T4014

Tobramycin

Oseltamivir impurity H European Pharmacopoeia (EP) Reference Standard

Y0001341

Oseltamivir impurity H

N-Acetylneuraminic Acid, 2,3-Dehydro-2-deoxy-, Sodium Salt Inhibitor of bacterial, viral, and mammalian neuraminidases. Ki = 4 µM for influenza virus neuraminidase. Believed to act by binding to the catalytic site of neuraminidase as a transition state analog.

Millipore

252926

N-Acetylneuraminic Acid, 2,3-Dehydro-2-deoxy-, Sodium Salt

Darunavir ≥98% (HPLC)

Sigma-Aldrich

SML0937

Darunavir

R H Beigi et al.
Clinical pharmacology and therapeutics, 98(4), 403-405 (2015-06-26)
Pregnancy heightens the risk of adverse outcomes from influenza infections. This is true for both seasonal epidemics as well as occasional pandemics. Seasonal influenza vaccines are the focus of disease prevention and are recommended for all pregnant women in any
Mohamed A Kamal et al.
Antimicrobial agents and chemotherapy, 59(9), 5388-5395 (2015-06-24)
A population drug-disease model was developed to describe the time course of influenza virus with and without oseltamivir treatment and to investigate opportunities for antiviral combination therapy. Data included viral titers from 208 subjects, across 4 studies, receiving placebo and
Brian E Davies
The Journal of antimicrobial chemotherapy, 65 Suppl 2, ii5-ii10 (2010-03-20)
Influenza is a transmissible viral pathogen that continues to cause substantial morbidity and mortality. Oseltamivir is an orally administered antiviral medication that selectively inhibits the influenza neuraminidase enzymes that are essential for viral replication. Treatment of infected children > or
Enkhtaivan Gansukh et al.
Food chemistry, 334, 127508-127508 (2020-07-28)
Quercetin, a potential polyphenolic which possesses several biological effects. The influenza virus polymerase basic 2 (PB2) subunit of RNA polymerase responsible for replication, degree of virus conservation and active target site for designing specific antivirals. The quercetin derivatives downloaded from

Nossa equipe de cientistas tem experiência em todas as áreas de pesquisa, incluindo Life Sciences, ciência de materiais, síntese química, cromatografia, química analítica e muitas outras.

Entre em contato com a assistência técnica