SML1335

Pidotimod

≥98% (HPLC)

• Sinônimo(s): (4R)-3-(5-Oxo-L-prolyl)-1,3-thiazolidine-4-carboxylic acid, (R)-3-((S)-5-Oxopyrrolidine-2-carbonyl)thiazolidine-4-carboxylic acid, (R)-3-[(S)-(5-Oxo-2-pyrrolidinyl) carbonyl]-thiazolidine-4-carboxylic acid, 3-L-Pyroglutamyl-L-thiaziolidine-4carboxylic acid, PGT/1A
• Fórmula empírica (Notação de Hill): C₉H₁₂N₂O₄S
• Número CAS: 121808-62-6
• Peso molecular: 244.27
• Número MDL: MFCD00867583
• Código UNSPSC: 12352200
• ID de substância PubChem: 329825793
• NACRES: NA.77

Propriedades

• Nível de qualidade: 100
• Ensaio: ≥98% (HPLC)
• Formulário: powder
• atividade óptica: [α]/D -135 to -155°, c = 1 in 6 M HCl
• cor: white to beige
• solubilidade: H₂O: 2 mg/mL, clear (warmed)
• temperatura de armazenamento: room temp
• cadeia de caracteres SMILES: OC([C@@H]1CSCN1C([C@H]2NC(CC2)=O)=O)=O
• InChI: 1S/C9H12N2O4S/c12-7-2-1-5(10-7)8(13)11-4-16-3-6(11)9(14)15/h5-6H,1-4H2,(H,10,12)(H,14,15)/t5-,6-/m0/s1
• chave InChI: UUTKICFRNVKFRG-WDSKDSINSA-N

Descrição

Ações bioquímicas/fisiológicas

Pidotimod is a dipeptide immunostimulant with biological activity on both the adaptive and the innate immune responses. Pidotimod has been reported to modulate airway epithelial cells functions involved in host-virus interaction possibly through NF-kB activation, promote functional maturation of dendritic cells, and facilitate M2 macrophage polarization and function. Pidotimod has been investigated for use to increase response to recurrent respiratory infections primarily in children.

Informações de segurança

• Código de classe de armazenamento: 11 - Combustible Solids
• Classe de risco de água (WGK): WGK 3
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable