SMB00292
Fengycin
≥90%
Sinônimo(s):
Fengycin, Plipastatin
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About This Item
Fórmula empírica (Notação de Hill):
C72H110N12O20
Peso molecular:
1463.71
Código UNSPSC:
51102829
NACRES:
NA.85
Produtos recomendados
fonte biológica
Bacillus subtilis
Ensaio
≥90%
forma
powder
cor
, Off-White to Light Yellow to Light Brown
espectro de atividade do antibiótico
fungi
Modo de ação
cell membrane | interferes
temperatura de armazenamento
2-8°C
Categorias relacionadas
Descrição geral
Chemical structure: peptide
Fengycin is a lipopeptide complex which is synthesized by Bacillus subtilis strain F-29-3. It is an antifungal compound, and is made up of two components namely, fengycin A and fengycin B. Fengycin A contains 1 D-Ala, 1 L-Ile, 1 L-Pro, 1 D-allo-Thr, 3 L-Glx, 1 D-Tyr, 1 L-Tyr, 1 D-Orn, whereas fengycin B contains D-Val instead of D-Ala.
Aplicação
Fengycin may be used for the sterilization of E. coli., and for the inactivation of spores of Bacillus cereus.
Ações bioquímicas/fisiológicas
Fengycin shows antifungal properties against filamentous fungi, but has no action against yeast and bacteria. Certain unsaturated fatty acids facilitate the antifungal property, whereas sterols, phospholipids and oleic acid act as antagonists. It produces morphological abnormalities in fungi including curling, bulging and empyting of hyphae. Thus, it mainly functions through its effects on the plasma membrane.
Embalagem
5MG
Armazenamento e estabilidade
Store at 2 to 8 °C. (Keep container tightly closed in a dry and well-ventilated place. Light sensitive.)
Outras notas
Keep container tightly closed in a dry and well-ventilated place. Light sensitive.
Código de classe de armazenamento
11 - Combustible Solids
Classe de risco de água (WGK)
WGK 3
Ponto de fulgor (°F)
Not applicable
Ponto de fulgor (°C)
Not applicable
Certificados de análise (COA)
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Antifungal effects of bacilysin and fengymycin from Bacillus subtilis F-29-3 a comparsion with activities of other Bacillus antibiotics.
Loeffler W., et al
Journal of Phytopathology, 115, 204-213 (1986)
Optimization of inactivation of endospores of Bacillus cereus in milk by surfactin and fengycin using a response surface method.
Huang X
International Journal of Peptide Research and Therapeutics, 14(2), 89-95 (2008)
Plipastatins: new inhibitors of phospholipase A2, produced by Bacillus cereus BMG302-fF67
Nishikiori, T., et al
The Journal of Antibiotics, 39, 745-745 (1986)
Marc Ongena et al.
Environmental microbiology, 9(4), 1084-1090 (2007-03-16)
Multiple strains of Bacillus spp. were demonstrated to stimulate plant defence responses. However, very little is known about the nature of molecular determinants secreted by these Gram-positive bacteria that are responsible for the elicitation of the induced systemic resistance (ISR)
N Vanittanakom et al.
The Journal of antibiotics, 39(7), 888-901 (1986-07-01)
Fengycin is an antifungal lipopeptide complex produced by Bacillus subtilis strain F-29-3. It inhibits filamentous fungi but is ineffective against yeast and bacteria. The inhibition is antagonized by sterols, phospholipids and oleic acid, whereas two other unsaturated fatty acids increase
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