S3523

Surfactin

from Bacillus subtilis, ≥98.0% (HPLC)

• Sinônimo(s): surfactin C
• Fórmula empírica (Notação de Hill): C₅₃H₉₃N₇O₁₃
• Número CAS: 24730-31-2
• Peso molecular: 1036.34
• Código UNSPSC: 51102829
• ID de substância PubChem: 24899562
• NACRES: NA.85

Propriedades

• fonte biológica: Bacillus subtilis
• Nível de qualidade: 200
• descrição: zwitterionic
• Ensaio: ≥98.0% (HPLC)
• Formulário: powder
• condição de armazenamento: (Keep container tightly closed in a dry and well-ventilated place. Keep in a dry place.)
• cor: white to faint yellow
• CMC: 7.5-20 μmol/L (depending on methods)
• solubilidade: ethanol: soluble 10 mg/mL
• espectro de atividade do antibiótico: Gram-negative bacteria; Gram-positive bacteria; fungi; mycoplasma; neoplastics; viruses
• Modo de ação: cell membrane | interferes
• temperatura de armazenamento: 2-8°C
• cadeia de caracteres SMILES: CC(C)CCCCCCCCC[C@@H]1CC(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)O1
• InChI: 1S/C53H93N7O13/c1-30(2)20-18-16-14-13-15-17-19-21-36-28-43(61)54-37(22-23-44(62)63)47(66)55-38(24-31(3)4)48(67)57-40(26-33(7)8)51(70)60-46(35(11)12)52(71)58-41(29-45(64)65)50(69)56-39(25-32(5)6)49(68)59-42(27-34(9)10)53(72)73-36/h30-42,46H,13-29H2,1-12H3,(H,54,61)(H,55,66)(H,56,69)(H,57,67)(H,58,71)(H,59,68)(H,60,70)(H,62,63)(H,64,65)/t36-,37+,38+,39-,40-,41+,42+,46+/m1/s1
• chave InChI: NJGWOFRZMQRKHT-WGVNQGGSSA-N

Descrição

Descrição geral

Chemical structure: peptide

Aplicação

Surfactin is used as a surfactant to mediate flux of mono-and divalent cations, such as calcium, across lipid bilayer membranes. It is also used to study antitumor activity, activity against enveloped viruses, activity against the protoplast of Bacillus megaterium and the activity against Mycoplasma.

Ações bioquímicas/fisiológicas

Surfactin is a lipopeptide antibiotic that is composed of one β-hydroxy fatty acid, which has a long fatty acid moiety, and seven amino acids. Three of them have D configurations. It is a powerful biosurfactant that causes lysis of erythrocytes and bacteria. It is also a clotting inhibitor. Surfactin is thought to disrupt or disintegrate membranes via physicochemical interaction with the membranes.

Outras notas

Keep container tightly closed in a dry and well-ventilated place. Keep in a dry place.

Informações de segurança

• Código de classe de armazenamento: 11 - Combustible Solids
• Classe de risco de água (WGK): WGK 3
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable
• Equipamento de proteção individual: Eyeshields, Gloves, type N95 (US)