SBR00041

Cefiderocol

• Sinônimo(s): S-649266
• Fórmula empírica (Notação de Hill): C₃₀H₃₄ClN₇O₁₀S₂
• Número CAS: 1225208-94-5
• Peso molecular: 752.21
• Número MDL: MFCD30533432
• Código UNSPSC: 12352111
• NACRES: NA.76

Propriedades

• Ensaio: ≥95% (HPLC)
• Nível de qualidade: 100
• forma: solid
• adequação da reação: reagent type: chelator
• espectro de atividade do antibiótico: Gram-negative bacteria
• Modo de ação: protein synthesis | inhibits
• temperatura de armazenamento: −20°C
• cadeia de caracteres SMILES: NC1=NC(/C(C(N[C@@H]2C(N3[C@@H]2SCC(C[N+]4(CCCC4)CCNC(C5=CC=C(O)C(O)=C5Cl)=O)=C3C([O-])=O)=O)=O)=N/OC(C(O)=O)(C)C)=CS1
• InChI: 1S/C30H34ClN7O10S2/c1-30(2,28(46)47)48-36-19(16-13-50-29(32)34-16)24(42)35-20-25(43)37-21(27(44)45)14(12-49-26(20)37)11-38(8-3-4-9-38)10-7-33-23(41)15-5-6-17(39)22(40)18(15)31/h5-6,13,20,26H,3-4,7-12H2,1-2H3,(H7-,32,33,34,35,36,39,40,41,42,44,45,46,47)/t20-,26-/m1/s1
• chave InChI: DBPPRLRVDVJOCL-FQRUVTKNSA-N

Descrição

Descrição geral

Cefiderocol has been shown to be effective in preventing the emergence of resistant mutants but is not active against methicillin-resistant Staphylococcus aureus (MRSA) or colistin-resistant bacteria. This versatile compound finds applications in cell biology and biochemical research.

Cefiderocol is a novel injectable siderophore cephalosporin, which was formerly known as S-649266. It has a catechol-type siderophore and cephalosporin core and side chains. Cefiderocol has structural similarity with both ceftazidime and cefepime, besides the chlorocatechol group on the end of the C-3 chain.

Aplicação

Cefiderocol has been used:

• study bacterial infections and tracking their uptake in vivo
• the study of the activity of Cefiderocol against gram-negative bacteria

Ações bioquímicas/fisiológicas

Mode of Action: Cefiderocol binds to specific proteins called penicillin-binding proteins (PBPs) located on the bacterial cell wall. This binding affinity inhibits the synthesis of the bacterial cell wall, leading to cell lysis and bacterial death.

Antimicrobial Spectrum: Cefiderocol has strong antimicrobial properties, especially against a wide spectrum of Gram-negative pathogens. Due to its siderophore core it is also a natural iron-chelator, which adds to its antibacterial activities.

Características e benefícios

• High-quality antibiotic suitable for multiple research applications
• Ideal for Cell Biology and Biochemical research

Outras notas

For additional information on our range of Biochemicals, please complete this form.

Exoneração de responsabilidade

The product is not intended for use as a biocide under global biocide regulations, including but not limited to US EPA′s Federal Insecticide Fungicide and Rodenticide Act, European Biocidal Products Regulation, Canada’s Pest Management Regulatory Agency, Turkey’s Biocidal Products Regulation, Korea’s Consumer Chemical Products and Biocide Safety Management Act (K-BPR) and others.

Informações de segurança

• Código de classe de armazenamento: 11 - Combustible Solids
• Classe de risco de água (WGK): WGK 3
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable