SAB5700296

Anti-Phospho-ERBB4-Y1284 antibody produced in rabbit

• Sinônimo(s): ALS19, ERBB4, HER4, HER4/ErbB4, p180erbB4
• Código UNSPSC: 12352203
• NACRES: NA.43

Propriedades

• fonte biológica: rabbit
• Nível de qualidade: 100
• forma do anticorpo: affinity isolated antibody
• tipo de produto de anticorpo: primary antibodies
• clone: polyclonal
• forma: buffered aqueous solution
• peso molecular: 143; 145; 146
• reatividade de espécies: rat, mouse, human
• concentração: 2.55 mg/ml
• técnica(s): western blot: 1:500-1:2000
• nº de adesão UniProt: Q15303
• Condições de expedição: wet ice
• temperatura de armazenamento: −20°C
• modificação pós-traducional do alvo: phosphorylation (pTyr1284)
• Informações sobre genes: human ... ERBB4(2066)

Descrição

Descrição geral

This gene is a member of the Tyr protein kinase family and the epidermal growth factor receptor subfamily. It encodes a single-pass type I membrane protein with multiple cysteine rich domains, a transmembrane domain, a tyrosine kinase domain, a phosphotidylinositol-3 kinase binding site and a PDZ domain binding motif. The protein binds to and is activated by neuregulins and other factors and induces a variety of cellular responses including mitogenesis and differentiation. Multiple proteolytic events allow for the release of a cytoplasmic fragment and an extracellular fragment. Mutations in this gene have been associated with cancer. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized.

Imunogênio

A synthetic phosphorylated peptide around Y1284 of human ERBB4 (NP_005226.1).

forma física

PBS with 0.02% sodium azide,50% glycerol,pH7.3.

Armazenamento e estabilidade

Store at -20℃. Avoid freeze / thaw cycles.

Informações de segurança

• Código de classe de armazenamento: 12 - Non Combustible Liquids
• Classe de risco de água (WGK): WGK 1
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable