SAB5600047

Anti-BRAF (V600E) antibody, Rabbit monoclonal

recombinant, expressed in HEK 293 cells, clone RM8, purified immunoglobulin

• Sinônimo(s): Anti-B-RAF1, Anti-B-raf, Anti-BRAF-1, Anti-BRAF1, Anti-NS7, Anti-RAFB1
• Código UNSPSC: 12352203
• NACRES: NA.41

Propriedades

• recombinante: expressed in HEK 293 cells
• Nível de qualidade: 100
• forma do anticorpo: purified immunoglobulin
• tipo de produto de anticorpo: primary antibodies
• clone: RM8, monoclonal; recombinant monoclonal
• Formulário: buffered aqueous glycerol solution
• reatividade de espécies: human
• concentração: ~1 mg/mL
• técnica(s): ELISA: 0.5-2 μg/mL; immunoblotting: 0.5-2 μg/mL; immunocytochemistry: 0.5-5 μg/mL; immunohistochemistry: 0.5-5 μg/mL
• Isotipo: IgG
• nº de adesão NCBI: 673
• nº de adesão UniProt: P15056
• Condições de expedição: wet ice
• temperatura de armazenamento: −20°C
• modificação pós-traducional do alvo: unmodified
• Informações sobre genes: human ... BRAF(673)

Descrição

Descrição geral

BRAF (B-Raf proto-oncogene) is a serine-threonine kinase, that codes for B-Raf protein. It is located on human chromosome 7q34.

Especificidade

This antibody reacts to the BRAF V600E mutant. No cross reactivity with wild type BRAF.

Imunogênio

Peptide corresponding to BRAF V600E mutant

Ações bioquímicas/fisiológicas

BRAF (B-Raf proto-oncogene) participates in signaling direct cell growth. It induces tumor growth by initiating the mitogen-activated protein kinase (MAPK) pathway in various tumors like cutaneous melanoma and carcinomas of the thyroid and colon.

Características e benefícios

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

forma física

Solution in phosphate buffered saline containing 50% glycerol, 1% BSA and 0.09% sodium azide.

Exoneração de responsabilidade

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informações de segurança

• Código de classe de armazenamento: 10 - Combustible liquids
• Classe de risco de água (WGK): WGK 2
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable